Guoyuan Sinopharm (Guangdong) Pharmaceutical Group Co., Ltd.

Dapoxetine hydrochloride tablets (specification: 60 mg) developed by Guoyuan Guoyao (Guangdong) Pharmaceutical Group Co., Ltd. were used as the test preparation, and dapoxetine hydrochloride tablets (trade name: Priligy®, specification: 60 mg) from Berlin-Chemie AG were used as the reference preparation. The pharmacokinetic parameters and relative bioavailability of the two preparations after single administration in the fasting and postprandial states were investigated to evaluate whether the two preparations were bioequivalent. At the same time, the safety and tolerability of the two preparations in healthy humans were evaluated.