Last update 13 Apr 2026

Shanghai Simnova Biotechnology Co.,Ltd.

Holding Company | Subsidiary Company|2020|Shanghai Shi, China|
www.simnovabio.com

Overview

Basic Info

Introduction
Shanghai Simnova Biotechnology Co., Ltd. is a clinical-stage biotechnology company specializing in the development of first-class cancer cell therapies. Supported by Simcere Pharmaceutical, Simnova Biotech was established in Boston, USA, in 2019, initiating early-stage drug research and layout for cell therapy. In 2021, Simnova Biotech spun off from Simcere Pharmaceutical to operate independently. By 2020, its GMP facility was constructed in Shanghai.

Tags

Neoplasms
Immune System Diseases
Hemic and Lymphatic Diseases
CAR-NK
CAR-T
Autologous CAR-T

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Neoplasms11
Hemic and Lymphatic Diseases4
Immune System Diseases4
Nervous System Diseases1
Top 5 Drug TypeCount
CAR-NK5
CAR-T3
Autologous CAR-T1
Fusion protein1
in vivo CAR-T therapy1
Top 5 TargetCount
CD19(B-lymphocyte antigen CD19)2
BCMA(B-cell maturation protein)2
EGFRvIII x HER2 x IL-13Rα21
DLL3(Delta-like protein 3)1
BCMA x GPRC5D1

Related

11
Drugs associated with Shanghai Simnova Biotechnology Co.,Ltd.
SNC110
Target-
Mechanism-
Active Org.
Shanghai Simnova Biotechnology Co.,Ltd.
Originator Org.
Shanghai Simnova Biotechnology Co.,Ltd.
Active Indication
Solid tumor
Inactive Indication-
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date-
SNC-102
Target
BCMA
Mechanism
BCMA inhibitors [+2]
Active Org.
Shenzhen Simnova Biotechnology Co.,Ltd. [+2]
Originator Org.
Shanghai Simnova Biotechnology Co.,Ltd.
Active Indication
Multiple Myeloma [+1]
Inactive Indication-
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date-
SNC-109
Target
EGFRvIII x HER2 x IL-13Rα2
Mechanism
EGFRvIII antagonists [+2]
Active Org.
Shanghai Simnova Biotechnology Co.,Ltd.
Originator Org.
Shanghai Simnova Biotechnology Co.,Ltd.
Active Indication
Glioblastoma Multiforme [+1]
Inactive Indication-
Drug Highest PhasePhase 1
First Approval Ctry. / Loc.-
First Approval Date-
9
Clinical Trials associated with Shanghai Simnova Biotechnology Co.,Ltd.
NCT06468683
/ Not yet recruitingPhase 1
A Phase I Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of F01 in Patients With Moderate-to-severe Refractory Systemic Lupus Erythematosus
NCT06384482
/ RecruitingPhase 1
To Evaluate the Safety and Pharmacokinetic of SNC115 Injections in Patients With Recurrent/Refractory Small Cell Lung Cancer and Lung Large Cell Neuroendocrine Crcinoma: an Open-label, Single-arm, Dose Escalation Exploratory Study
NCT06206902
/ Unknown statusPhase 1
A Multicenter, Open Phase I Study to Evaluate the Safety and Pharmacokinetic Profile of F01 in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma
100 Clinical Results associated with Shanghai Simnova Biotechnology Co.,Ltd.
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0 Patents (Medical) associated with Shanghai Simnova Biotechnology Co.,Ltd.
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1
Literatures (Medical) associated with Shanghai Simnova Biotechnology Co.,Ltd.
Cancer Biology & Medicine
Phase I clinical study of humanized BCMA-single-domain antibodies targeting CAR-T in patients with relapsed or refractory multiple myeloma
100 Deals associated with Shanghai Simnova Biotechnology Co.,Ltd.
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100 Translational Medicine associated with Shanghai Simnova Biotechnology Co.,Ltd.
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Pipeline

Pipeline Snapshot as of 01 May 2026

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Discovery
3
3
Preclinical
Phase 1
4
1
Phase 2
Other
6
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
SNC110
Solid tumor
More
Phase 2
SNC-103
 ( CD19 )		Systemic Lupus Erythematosus
More
Phase 1
SNC-109
 ( EGFRvIII x HER2 x IL-13Rα2 )		Glioblastoma Multiforme
More
Phase 1
SNC116
 ( CD19 )		B-cell lymphoma recurrent
More
Early Phase 1
SNC-112
 ( BCMA x GPRC5D )		Multiple Myeloma
More
Preclinical
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