Delving into the Latest Updates on Xi'an International Medical Center Co. Ltd. with Synapse

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Hemic and Lymphatic Diseases

Neoplasms

Natural Killer Cell Therapies

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Hemic and Lymphatic Diseases	1
Neoplasms	1

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Natural Killer Cell Therapies	1

Author: Wang, Juan ; Ye, Taosheng ; Li, Yishi ; Xu, Dongyang ; Xie, Fangfang ; Zou, Jun ; Luo, Zhuang ; Zhang, Nan ; Ye, Xianwei ; Tang, Chunli ; Hou, Gang ; Zhang, Jisong ; Wang, Tao ; Sun, Jiayuan ; Guan, Zhenbiao ; Zhao, Qi ; Zhang, Quncheng ; Chen, Zhongbo ; Xu, Wujian ; Xia, Yang ; Wu, Xuemei ; Chen, Hong ; Zheng, Xiaoxuan ; Zhang, Peng ; Shen, Yongchun ; Wan, Nansheng ; Yang, Huizhen ; Liu, Dan ; Chen, Enguo ; Li, Xuan ; Xiao, Kui ; Ji, Cheng ; Wang, Huaqi ; Lian, Hairong ; Yu, Pengfei ; Li, Wei ; Xu, Fei ; Ouyang, Haifeng ; Liao, Jiangrong ; Li, Haitao ; Yang, Junyong ; Shi, Yiwei ; Li, Manxiang ; Wang, Hong

AbstractCone‐beam computed tomography (CBCT) system can provide real‐time 3D images and fluoroscopy images of the region of interest during the operation. Some systems can even offer augmented fluoroscopy and puncture guidance. The use of CBCT for interventional pulmonary procedures has grown significantly in recent years, and numerous clinical studies have confirmed the technology's efficacy and safety in the diagnosis, localization, and treatment of pulmonary nodules. In order to optimize and standardize the technical specifications of CBCT and guide its application in clinical practice, the consensus statement has been organized and written in a collaborative effort by the Professional Committee on Interventional Pulmonology of China Association for Promotion of Health Science and Technology.

01 Feb 2024·Journal of Cardiovascular Translational Research

Cardiac Metabolism, Reprogramming, and Diseases

Review

Author: Lu, Zuocheng ; Shen, Min ; Lin, Jie ; Zhang, Xuan ; Jia, Tengfei ; Guo, Baolin ; Sun, Dongdong ; Feng, Jiaxu ; Liu, Yue ; Wang, Haichang ; Chen, Yanyan ; Shu, Xiaofei ; Zhang, Jiye

Cardiovascular diseases (CVD) account for the largest bulk of deaths worldwide, posing a massive burden on societies and the global healthcare system. Besides, the incidence and prevalence of these diseases are on the rise, demanding imminent action to revert this trend. Cardiovascular pathogenesis harbors a variety of molecular and cellular mechanisms among which dysregulated metabolism is of significant importance and may even proceed other mechanisms. The healthy heart metabolism primarily relies on fatty acids for the ultimate production of energy through oxidative phosphorylation in mitochondria. Other metabolites such as glucose, amino acids, and ketone bodies come next. Under pathological conditions, there is a shift in metabolic pathways and the preference of metabolites, termed metabolic remodeling or reprogramming. In this review, we aim to summarize cardiovascular metabolism and remodeling in different subsets of CVD to come up with a new paradigm for understanding and treatment of these diseases.

17 Nov 2023·Medicine

Operative timing and the safety of emergency laparoscopic cholecystectomy: A retrospective analysis

Article

Author: Huang, Qin-Xian ; Tian, Hong-Gang ; Xu, Ze-Yu ; Li, Guo-Cai ; Xu, Yong

The ideal operative timing for laparoscopic cholecystectomy (LC) remains controversial, particularly in emergency patients. This study aimed to evaluate the necessity of operative timing for emergency LC. One hundred ninety-four patients who had undergone operative timings were classified into groups of <72h and >72h from the onset of symptoms to the operation. Baseline data, basic disease, operative bleeding, complications, and conversion rates were analyzed by Variance analysis and logistic regression analysis. The total morbidity of postoperative complication was 4.93% and 3.84% (P = .751) in the <72h and >72h groups respectively. The complication and conversion to LC were mainly influenced by age and gallbladder volume (odds ratio [OR] = 1.078, P = .013, and OR = 1.035, P = .031), but not by operative timing (P = .292). The intraoperative blood loss was closely correlated with the gallbladder volume (OR = 1.019, P = .025) by logit regression analysis, and correlation coefficient of R = 0.436, P < .01. Our results suggest that it is not necessary to confine the operative timing of LC to within 72h from the onset of symptoms, and gallbladder volume should be emphasized in the operative timing for emergency LC.

100 Deals associated with Xi'an International Medical Center Co. Ltd.

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100 Translational Medicine associated with Xi'an International Medical Center Co. Ltd.

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Pipeline

Pipeline Snapshot as of 26 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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