Delving into the Latest Updates on Hefei Yifan Biological Pharmaceutical Co., Ltd. with Synapse

Overview

Tags

Nervous System Diseases

Immune System Diseases

Hemic and Lymphatic Diseases

Herbal medicine

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

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Disease Domain	Count

Hemic and Lymphatic Diseases	1
Immune System Diseases	1
Infectious Diseases	1
Nervous System Diseases	1
Neoplasms	1

Top 5 Drug Type	Count

Herbal medicine	1
Small molecule drug	1

Top 5 Target	Count

CXCR4 x Chemokine receptors	1

"主要研究目的：按有关生物等效性试验的规定，选择日本興和株式会社为持证商的富马酸依美斯汀缓释胶囊（商品名：REMICUT；规格：2mg）为参比制剂，对四川德峰药业有限公司生产提供的受试制剂富马酸依美斯汀缓释胶囊（规格：2mg）进行空腹和餐后给药人体生物等效性试验，比较受试制剂中药物的吸收速度和吸收程度与参比制剂的差异是否在可接受的范围内，评价两种制剂在空腹和餐后给药条件下的生物等效性。次要研究目的：观察中国健康受试者服用受试制剂富马酸依美斯汀缓释胶囊（规格：2mg）和参比制剂富马酸依美斯汀缓释胶囊（商品名：REMICUT；规格：2mg）后的安全性。

[Translation]

"Main research purpose: According to the regulations on bioequivalence testing, select emestine fumarate sustained-release capsules (trade name: REMICUT; specification: 2 mg) of Japan Kowa Co., Ltd. as the licensee as the reference preparation , conduct human bioequivalence tests on fasting and postprandial administration of the test preparation emestine fumarate sustained-release capsules (specification: 2 mg) produced and provided by Sichuan Defeng Pharmaceutical Co., Ltd., and compare the drugs in the test preparation Whether the difference in absorption rate and degree of absorption from the reference preparation is within the acceptable range, evaluate the bioequivalence of the two preparations under fasting and postprandial administration conditions. Secondary research purpose: To observe Chinese healthy subjects taking the test preparation emedestine fumarate sustained-release capsules (specification: 2 mg) and the reference preparation emedestine fumarate sustained-release capsules (trade name: REMICUT; Specification: 2mg) after safety.

Start Date02 Jan 2023

Sponsor / Collaborator

Sichuan Defeng Pharmaceutical Co., Ltd.

CTR20220451 / RecruitingPhase 2

评价复方银花解毒颗粒治疗儿童流行性感冒（风热证）的有效性和安全性的随机、双盲、安慰剂平行对照、多中心Ⅱ期临床试验

[Translation] A randomized, double-blind, placebo-controlled, multicenter phase II clinical trial to evaluate the efficacy and safety of compound Yinhua Jiedu granules in the treatment of influenza (wind-heat syndrome) in children

主要目的：初步评价复方银花解毒颗粒治疗儿童流行性感冒（风热证）的有效性。次要目的：初步评价复方银花解毒颗粒治疗儿童流行性感冒（风热证）的安全性。

[Translation]

Main purpose: To preliminarily evaluate the effectiveness of Compound Yinhua Jiedu Granules in treating influenza (wind-heat syndrome) in children. Secondary purpose: To preliminarily evaluate the safety of Compound Yinhua Jiedu Granules in treating influenza (wind-heat syndrome) in children.

Start Date11 Dec 2022

Sponsor / Collaborator

Tianchang Yifan Pharmaceutical Co., Ltd.

100 Clinical Results associated with Hefei Yifan Biological Pharmaceutical Co., Ltd.

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0 Patents (Medical) associated with Hefei Yifan Biological Pharmaceutical Co., Ltd.

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5

Literatures (Medical) associated with Hefei Yifan Biological Pharmaceutical Co., Ltd.

01 Jan 2023·Journal of Colloid and Interface Science

Optimized mesopores enable enhanced capacitance of electrochemical capacitors using ultrahigh surface area carbon derived from waste feathers

Article

Author: Hu, Guangzhou ; Chen, Chong ; Bian, Zhentao ; Wang, Hongyan ; Zhao, Xuanxuan ; Ni, Zhonghai ; Komarneni, Sridhar ; Zhao, Guangzhen

Porous carbons with high specific surface area are critical engineering materials for current electrochemical capacitors (ECs) technology. Controlling the pore size distribution of porous carbons remains a significant challenge as it is a key aspect in many applications. Herein, we synthesized porous carbon as the electrode material of ECs by means of a two-step synthesis procedure using abandoned feathers as carbon precursor and potassium hydroxide as activating agent. The optimal sample (AFHPC-800-1:3) exhibited an ultra-high specific surface area (S_BET) of 3474 m²/g and a huge total pore volume (V_T) of 1.82 m³ g^-1 as well as abundant small mesopores ranging from 2 to 5 nm in size. The ECs based on the AFHPC-800-1:3 electrode exhibited an ultra-high specific capacitance (C_sp) of up to 709F g^-1 at 0.5 A g^-1. More interestingly, a capacitance of 212F g^-1 was retained even at 100 A g^-1, demonstrating excellent high-rate capacitive performance. Furthermore, the symmetrical capacitor yielded an excellent energy density of 35.1 Wh kg^-1 when the specific power density was 625 W kg^-1, substantiating the potential of the small mesopores in promoting the overall capacitance and energy density of electrode materials.

Liaoning Huagong

Study on extraction technology of bilirubin from pig bile

Author: Lu, Hong-bao ; Li, Kai ; Guo, Qing

Bilirubin was extracted from pig bile by hydrolysis.The effects of antioxidant dosage, alk. hydrolysis pH, hydrolysis temperature and time, acidification pH on the extraction rate and content of bilirubin were studied.The results showed that the optimal extraction conditions of bilirubin by hydrolyzing method were as follows: dosage of antioxidant was 0.5%, pH of alk. hydrolysis was 11.0∼11.5, hydrolysis temperature was 75∼80°C, time was 10 min, pH of acidification was 5.5∼6.0, the extraction rate of bilirubin was 95%, the content was more than 98.0%.

RSC Advances

Hierarchical hollow-tubular porous carbon microtubes prepared via a mild method for supercapacitor electrode materials with high volumetric capacitance

Article

Author: Wang, Hongyan ; Wang, Qianli ; Song, Lei ; Wang, Zhicheng ; Chu, Juncai ; Bian, Zhentao ; Liu, Jianmin ; Zhao, Xuanxuan ; Xiao, Xuan ; Liu, Xinru

In this paper, hollow-tubular porous carbons were synthesized from abundant biomass Cycas fluff (CF) through simple carbonization followed by an NaHCO3 mild activation process.

100 Deals associated with Hefei Yifan Biological Pharmaceutical Co., Ltd.

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100 Translational Medicine associated with Hefei Yifan Biological Pharmaceutical Co., Ltd.

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Pipeline

Pipeline Snapshot as of 28 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Phase 3 Clinical

2

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