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100 Clinical Results associated with ESTRIGENIX THERAPEUTICS, INC.
0 Patents (Medical) associated with ESTRIGENIX THERAPEUTICS, INC.
A Scalable, Chromatography-Free Synthesis of the Potent and Highly Selective ERβ Agonist EGX358
Author: Chaudhury, Subhabrata ; Wetzel, Edward A. ; Donaldson, William A. ; Thennakoon, Dulanjali
Abstract4-[trans-4-(Hydroxymethyl)cyclohexyl]phenol (EGX358) is a potent and highly selective estrogen receptor beta (ERβ) agonist which has demonstrated efficacy for moderation of a chemically induced hot flash and for memory consolidation in an ovariectomized mouse model for menopause. An improved synthetic route to EGX358 is reported which proceeds in four steps and which is chromatography-free.
100 Deals associated with ESTRIGENIX THERAPEUTICS, INC.
100 Translational Medicine associated with ESTRIGENIX THERAPEUTICS, INC.