Last update 01 Nov 2024

JMackem Co., Ltd

South Korea
|
jmackem.com

Overview

Tags

Nervous System Diseases
Endocrinology and Metabolic Disease
Neoplasms
Chemical drugs

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Nervous System Diseases6
Endocrinology and Metabolic Disease1
Neoplasms1
Top 5 Drug TypeCount
Chemical drugs6
Unknown1
Top 5 TargetCount
5-HT receptor x GlyT21
HSP90(Heat shock 90kDa proteins)1
NLRP3(NACHT, LRR and PYD domains-containing protein 3)1
TRPV1 x μ opioid receptor1
QPCT(Glutaminyl-peptide cyclotransferase)1

Related

7
Drugs associated with JMackem Co., Ltd
AJH-2947
Target-
Mechanism-
Active Org.
JMackem Co., Ltd
Originator Org.
JMackem Co., Ltd
Active Indication
Diabetic Neuropathies [+1]
Inactive Indication-
Drug Highest PhasePhase 1
First Approval Ctry. / Loc.-
First Approval Date-
TRPV1+ μ agonist(JMackem)
Target
TRPV1 x μ opioid receptor
Mechanism
TRPV1 agonists [+1]
Active Org.
JMackem Co., Ltd
Originator Org.
JMackem Co., Ltd
Active Indication
Pain
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date-
NLRP3 regulators(JMackem)
Target
NLRP3
Mechanism
NLRP3 modulators
Active Org.
JMackem Co., Ltd
Originator Org.
JMackem Co., Ltd
Active Indication
Alzheimer Disease
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date-
1
Clinical Trials associated with JMackem Co., Ltd
NCT06155487 / Enrolling by invitationPhase 1
A Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose, Phase 1 Clinical Trial to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability After Oral Administration of AJH-2947 in Healthy Korean or Caucasian Male Subjects
100 Clinical Results associated with JMackem Co., Ltd
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0 Patents (Medical) associated with JMackem Co., Ltd
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100 Deals associated with JMackem Co., Ltd
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100 Translational Medicine associated with JMackem Co., Ltd
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Pipeline

Pipeline Snapshot as of 25 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Preclinical
6
1
Phase 1 Clinical
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
AJH-2947
Diabetic Neuropathies
More
Phase 1
HSP90 inhibitors(JMackem)
 ( HSP90 )		Neoplasms
More
Preclinical
TRPV1 antagonist prodrug(JMackem)
 ( TRPV1 )		Pain
More
Preclinical
NLRP3 regulators(JMackem)
 ( NLRP3 )		Alzheimer Disease
More
Preclinical
JM295
 ( 5-HT receptor x GlyT2 )		Pain
More
Preclinical
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