[Translation] A randomized, double-blind, placebo-controlled phase I/II study evaluating the safety and preliminary efficacy of a single interbody topical administration of AGA111 in patients with degenerative disc disease undergoing interbody fusion surgery
主要目的:
评估脊柱单节段椎体间单次给予AGA111的安全性。
次要目的:
评估脊柱单节段椎体间单次给予AGA111的药代动力学特征。
评估脊柱单节段椎体间单次给予AGA111的初步疗效。
[Translation] main purpose:
To evaluate the safety of single-segment interbody administration of AGA111 in the spine.
Secondary purpose:
To evaluate the pharmacokinetics of a single dose of AGA111 in a single interbody of the spine.
To evaluate the preliminary efficacy of a single dose of AGA111 in a single segment of the spine.