[Translation] A multicenter, randomized, double-blind, placebo-controlled clinical study on the immunoprotective mechanism of ICVAX (injectable nucleic acid for the treatment of HIV).
主要目的:研究治疗用艾滋病核酸注射液(ICVAX)免疫保护机制。
次要目的:
评估治疗用艾滋病核酸注射液(ICVAX)抑制HIV-1 RNA病毒载量的有效性;
评估ICVAX联合ART治疗在分析性治疗中断(Analytical treatment interruption,ATI)研究中的安全性。
探索性目的:深入探索ICVAX 免疫保护机制和病毒学相关机制。
[Translation] Primary Objective: To investigate the immunoprotective mechanism of therapeutic HIV nucleic acid injection (ICVAX).
Secondary Objectives: To evaluate the efficacy of therapeutic HIV nucleic acid injection (ICVAX) in suppressing HIV-1 RNA viral load; to evaluate the safety of ICVAX in combination with ART in an analytical treatment interruption (ATI) study.
Exploratory Objectives: To further explore the immunoprotective mechanism and virological mechanisms of ICVAX.