Zhejiang Fenghua Pharmaceutical Technology Co., Ltd.

Primary objective: To evaluate the safety of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia; To evaluate the pharmacokinetic characteristics of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia. Secondary objective: To evaluate the preliminary effectiveness of glycopyrrolate neostigmine injection at different doses in reversing the residual muscle relaxant effect of non-depolarizing muscle relaxants in Chinese patients after general anesthesia.

The orodisintegrating tablets of phloroglucinol provided by Zhejiang Fenghua Pharmaceutical Technology Co., Ltd. were used as the test preparation, and the orodisintegrating tablets of phloroglucinol certified by Teva Sante were used as the reference preparation to evaluate the relative bioavailability and bioequivalence in humans.

Main objective: To evaluate the bioequivalence of the leprocaine cream produced by Zhejiang Fenghua Pharmaceutical Technology Co., Ltd. as the test preparation and the leprocaine cream produced by Aspen Pharma Trading Limited as the reference preparation in humans.