[Translation] A phase III clinical trial of a multicenter, randomized, double-blind, placebo-controlled design to evaluate the protective efficacy of live attenuated herpes zoster vaccine in Chinese population aged 40 years and older
主要目的:评价接种疫苗30天后预防带状疱疹的保护效力。 次要目的: 1.评价接种疫苗后预防带状疱疹和预防/减轻PHN的保护效力; 2.评价接种疫苗30天后预防/减轻PHN和预防/减轻重度带状疱疹相关急性期疼痛(ZBPI评分≥3)的保护效力; 3.评价接种疫苗后的安全性、免疫原性和免疫持久性。
[Translation] Main objective: To evaluate the protective efficacy against shingles 30 days after vaccination. Secondary objectives: 1. To evaluate the protective efficacy of shingles prevention and prevention/relief of PHN after vaccination; 2. To evaluate the prevention/reduction of PHN and the prevention/reduction of severe shingles-related acute pain (ZBPI score ≥ 30 days after vaccination) 3) Protective efficacy; 3. Evaluate the safety, immunogenicity and immunity persistence after vaccination.