Beijing Wannianchun Biological Medicine High Technology Co., Ltd.

To study the effect of oral edenafil citrate tablets on the antihypertensive effect of nifedipine controlled-release tablets in Chinese male hypertensive subjects and the safety of their combined use.

To study the pharmacokinetic characteristics, tolerability and safety of multiple oral administration of 30 mg edenafil citrate tablets in healthy Chinese subjects.

To study the effect of oral clarithromycin on the pharmacokinetic characteristics of ardenafil citrate tablets in healthy Chinese male subjects and the safety of their combined use. To study the effect of oral rifampicin on the pharmacokinetic characteristics of ardenafil citrate tablets in healthy Chinese male subjects and the safety of their combined use. To study the effect of oral cimetidine on the pharmacokinetic characteristics of ardenafil citrate tablets in healthy Chinese male subjects and the safety of their combined use.