Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd

Main purpose: To compare the besulbetastin orally disintegrating tablets (specification: 10 mg) provided by Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd. and the besulbetastin produced by Tagbe Mitsubishi Pharmaceutical Co., Ltd. under fasting and postprandial administration conditions. Differences in the degree and rate of absorption of Stine orally disintegrating tablets (trade name: Talion®, strength: 10 mg) in healthy adult populations to evaluate its bioequivalence. Secondary purpose: To evaluate the safety of betastine besilate orally disintegrating tablets (specification: 10 mg) provided by Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd. under fasting and postprandial administration conditions.

Main purpose: 1. To study the difference between the test preparation idecalcidol soft capsule (specification: 0.75 μg, provided by Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd.) and the reference preparation idecalcitol soft capsule (Edirol) in a single oral administration in the fasting state. ; Specification: 0.75μg; Licensee: Chugai Separation Co., Ltd.), by comparing the pharmacokinetic parameters of the test preparation and the reference preparation in vivo absorption and metabolism of healthy subjects under fasting conditions, the human biological properties of the two preparations are evaluated. effectiveness. 2. Study the single oral administration of the test preparation idecalcitol soft capsule (specification: 0.75 μg, provided by Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd.) and the reference preparation idecalcitol soft capsule (Edirol?) in the postprandial state; Specification: 0.75μg; Licensee: Chugai Seisakusho Co., Ltd.), by comparing the pharmacokinetic parameters of the test preparation and the reference preparation in vivo absorption and metabolism of healthy subjects under postprandial conditions, the human biological properties of the two preparations are evaluated. effectiveness. Secondary purpose: To evaluate the safety of Chinese healthy subjects after a single oral administration of the test preparation idecalcitol soft capsules and the reference preparation idecalcitol soft capsules in fasting and postprandial states.

To compare the differences in absorption extent and rate between Cefdinir Granules (specification: 50 mg/0.5 g) provided by Guangzhou Jiangzheng Pharmaceutical Technology Co., Ltd. and Cefdinir Granules (trade name: Cefzon®, specification: 50 mg/0.5 g) certified by LTL Pharmaceutical Co., Ltd. in healthy adults under fasting and postprandial administration conditions, and evaluate their bioequivalence.