Beijing Handian Pharmaceutical Co. Ltd.

Primary study objective: To conduct a human pharmacokinetic study using amlodipine besylate tablets produced by Beijing Handian Pharmaceutical Co., Ltd. as the test formulation T and Norvasc® produced by Pfizer Pharmaceuticals LLC as the reference formulation R under fasting and fed conditions to evaluate the bioequivalence of the test formulation and the reference formulation in healthy Chinese subjects. Secondary study objective: To evaluate the safety of amlodipine besylate tablets in healthy Chinese subjects when taken on an empty stomach or after a meal

Primary study objective To conduct a human pharmacokinetic study under fasting and fed conditions to evaluate the bioequivalence of the test formulation with the reference formulation in healthy Chinese subjects Secondary study objective To evaluate the safety of levamlodipine besylate in healthy Chinese subjects when taken on a fasting or fed basis

The primary study objective was to evaluate the bioequivalence of the test and reference preparations in the fasting and fed state. The secondary study objective was to observe the safety of the test and reference preparations in healthy Chinese subjects.