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MechanismM4 receptor antagonists |
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Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
左旋盐酸去甲基苯环壬酯片在早、中期帕金森病患者中的安全性、耐受性和药代动力学Ⅰ期临床研究
[Translation] Phase I clinical study on the safety, tolerability and pharmacokinetics of levorotatory demethylphencyclonate hydrochloride tablets in patients with early and middle stage Parkinson's disease
主要目的:评价LS001在早、中期帕金森病患者中的安全性、耐受性。
次要目的:评价LS001在早、中期帕金森病患者中的药代动力学特征和疗效;探索左旋盐酸去甲基苯环壬酯在帕金森病患者体内的代谢产物。
[Translation] Primary purpose: To evaluate the safety and tolerability of LS001 in patients with early and middle stage Parkinson's disease.
Secondary purpose: To evaluate the pharmacokinetic characteristics and efficacy of LS001 in patients with early and middle stage Parkinson's disease; to explore the metabolites of L-demethylphencyclonate hydrochloride in patients with Parkinson's disease.
左旋盐酸去甲基苯环壬酯片(LS001)治疗早、中期帕金森病的随机、双盲、安慰剂对照的剂量探索和耐受性研究
[Translation] A randomized, double-blind, placebo-controlled, dose-finding and tolerability study of LS001 in the treatment of early and mid-stage Parkinson's disease
主要目的:评价LS001在早、中期帕金森病患者中的安全性和耐受性
次要目的:评价LS001治疗早、中期帕金森病的初步有效性以及在早、中期帕金森病群体药代动力学特征
[Translation] Primary objective: To evaluate the safety and tolerability of LS001 in patients with early and middle stage Parkinson's disease
Secondary objective: To evaluate the preliminary efficacy of LS001 in the treatment of early and middle stage Parkinson's disease and its pharmacokinetic characteristics in the early and middle stage Parkinson's disease population
左旋盐酸去甲基苯环壬酯片在健康受试者中的食物影响研究
[Translation] Study on the food effect of L-demethylphencyclonate hydrochloride tablets in healthy subjects
主要目的:观察在中国健康成年受试者中食物对LS001药代动力学特征的影响。
次要目的:评价LS001在健康受试者中空腹/餐后服用的安全性; 评价LS001在健康受试者中空腹给药后代谢产物的药代动力学特征。
[Translation] Primary objective: To observe the effect of food on the pharmacokinetic characteristics of LS001 in healthy adult subjects in China.
Secondary objective: To evaluate the safety of LS001 in healthy subjects after fasting/postprandial administration; To evaluate the pharmacokinetic characteristics of metabolites of LS001 after fasting administration in healthy subjects.
100 Clinical Results associated with Beijing Lansheng Pharmaceutical Technology Co., Ltd.
0 Patents (Medical) associated with Beijing Lansheng Pharmaceutical Technology Co., Ltd.
100 Deals associated with Beijing Lansheng Pharmaceutical Technology Co., Ltd.
100 Translational Medicine associated with Beijing Lansheng Pharmaceutical Technology Co., Ltd.