Delving into the Latest Updates on Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd. with Synapse

Overview

Tags

Digestive System Disorders

Infectious Diseases

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

No Data

Disease Domain	Count

Infectious Diseases	1

Top 5 Drug Type	Count

Small molecule drug	1

主要目的：评价MBT-1316 片在健康受试者中单次给药的安全性和耐受性，评价MBT-1316 片在健康受试者中多次给药的安全性和耐受性；次要目的：评价MBT-1316 片在健康受试者中单次给药的药代动力学特征，评价MBT-1316 片在健康受试者中多次给药的药代动力学特征，评价食物对MBT-1316 片药代动力学的影响以及探索MBT-1316 药物代谢转化特征。

[Translation]

Primary purpose: To evaluate the safety and tolerability of MBT-1316 tablets after single administration in healthy subjects, and to evaluate the safety and tolerability of MBT-1316 tablets after multiple administration in healthy subjects; Secondary purpose: To evaluate the pharmacokinetic characteristics of MBT-1316 tablets after single administration in healthy subjects, and to evaluate the pharmacokinetic characteristics of MBT-1316 tablets after multiple administration in healthy subjects, and to evaluate the effect of food on the pharmacokinetics of MBT-1316 tablets, and to explore the drug metabolic transformation characteristics of MBT-1316.

Start Date21 Jul 2023

Sponsor / Collaborator

Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

CTR20223380 / RecruitingPhase 1

评价MBT-1316 片在慢性乙型肝炎患者中多剂量单次、多次给药的安全性、耐受性、药效学、药代动力学特征的Ib 期临床试验

[Translation] Phase Ib clinical trial to evaluate the safety, tolerability, pharmacodynamics, and pharmacokinetic characteristics of MBT-1316 tablets in patients with chronic hepatitis B after single and multiple doses

主要目的：评价MBT-1316 片在慢性乙型肝炎患者中单次给药的安全性和耐受性；评价MBT-1316 片在慢性乙型肝炎患者中多次给药的安全性和耐受性。次要目的：评价MBT-1316 片在慢性乙型肝炎患者中多次给药的药效学特征；评价MBT-1316 片在慢性乙型肝炎患者中单次给药的药代动力学特征；评价MBT-1316 片在慢性乙型肝炎患者中多次给药的药代动力学特征。

[Translation]

Primary objective: To evaluate the safety and tolerability of MBT-1316 tablets after single administration in patients with chronic hepatitis B; To evaluate the safety and tolerability of MBT-1316 tablets after multiple administration in patients with chronic hepatitis B. Secondary objective: To evaluate the pharmacodynamic characteristics of MBT-1316 tablets after multiple administration in patients with chronic hepatitis B; To evaluate the pharmacokinetic characteristics of MBT-1316 tablets after single administration in patients with chronic hepatitis B; To evaluate the pharmacokinetic characteristics of MBT-1316 tablets after multiple administration in patients with chronic hepatitis B.

Start Date03 Apr 2023

Sponsor / Collaborator

Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

CTR20222348 / RecruitingPhase 1

评价MBT-1316片在健康受试者中多剂量单次、多次给药的安全性、耐受性、药代动力学特征及食物影响的Ia期临床试验

[Translation] Phase Ia clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and food effects of single and multiple doses of MBT-1316 tablets in healthy subjects

⑴主要目的：评价MBT-1316片在健康受试者中单次给药的安全性和耐受性和评价MBT-1316片在健康受试者中多次给药的安全性和耐受性；⑵次要目的：评价MBT-1316片在健康受试者中单次给药的药代动力学特征、评价MBT-1316片在健康受试者中多次给药的药代动力学特征、评价食物对MBT-1316片药代动力学的影响以及探索MBT-1316药物代谢转化特征。

[Translation]

⑴Main objective: To evaluate the safety and tolerability of a single dose of MBT-1316 tablets in healthy subjects and to evaluate the safety and tolerability of multiple doses of MBT-1316 tablets in healthy subjects; ⑵Secondary objectives: To evaluate the pharmacokinetic characteristics of a single dose of MBT-1316 tablets in healthy subjects, to evaluate the pharmacokinetic characteristics of multiple doses of MBT-1316 tablets in healthy subjects, to evaluate the effect of food on the pharmacokinetics of MBT-1316 tablets, and to explore the drug metabolic transformation characteristics of MBT-1316.

Start Date23 Sep 2022

Sponsor / Collaborator

Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

100 Clinical Results associated with Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

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0 Patents (Medical) associated with Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

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100 Deals associated with Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

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100 Translational Medicine associated with Beijing Junke Huayuan Pharmaceutical Technology Co., Ltd.

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Pipeline

Pipeline Snapshot as of 23 Dec 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

IND Approval

1

Phase 1 Clinical

Other

1

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

MBT-1316	Hepatitis B, Chronic More	Phase 1
HY-1608 ( OOR x μ opioid receptor )	Pain, Postoperative More	IND Approval
MBT-1805 ( PPARδ )	Liver Cirrhosis, Biliary More	Discontinued