The effect of eight weeks of gluteal muscle strengthening exercises on Sensorimotor Function, balance and ankle instability in women with chronic ankle instability

Start Date11 Nov 2023

Sponsor / Collaborator

Shahrekord University

IRCT20230908059379N1

/ RecruitingNot ApplicableIIT

The Effect of Eight Weeks of American National Academy of Sports Medicine (NASM) Corrective Exercises on the Improvement of Kypholordotic Deformity in Non-Athletic Female Students Aged 20-25 Years

Start Date26 Sep 2023

Sponsor / Collaborator

Shahrekord University

100 Clinical Results associated with Shahrekord University

0 Patents (Medical) associated with Shahrekord University

5,985

Literatures (Medical) associated with Shahrekord University

01 Jul 2025·Poultry Science

Effect of l-carnitine and emulsifier on growth performance, lipid profile, lipogenesis, and oxidative stress of broiler chickens raised at high altitude

Article

Author: Khajali, Fariborz ; Hassanpour, Hossein ; Ahmadipour, Behnam ; Hasani, Fathollah Farzam

High-altitude environments impose hypobaric hypoxia on broiler chickens, leading to pulmonary hypertension syndrome (PHS), oxidative stress, and impaired growth performance. l-carnitine, known for its role in energy metabolism and antioxidant properties, and emulsifiers, which enhance fat digestion, have the potential to mitigate these challenges. This study investigated the effects of l-carnitine and emulsifier supplementation, individually and in combination, on growth performance, lipid metabolism, oxidative stress, and gene expression in broilers raised at high altitudes. A total of 675 male broilers (Ross 308) were randomly assigned to nine dietary treatments, including control, l-carnitine (50 or 100 mg/kg), emulsifier (1 or 2 g/kg), and their combinations. Growth performance, carcass traits, serum lipid profiles, hepatic enzyme activities, oxidative stress markers, and gene expression (CPT1, CPT2, SOD1, iNOS) were evaluated over 42 days. Supplementation with l-carnitine and emulsifier improved weight gain and feed conversion ratio, and reduced feed intake. Carcass yield increased, and abdominal fat decreased significantly in treated groups. l-carnitine reduced serum cholesterol, triglycerides, and LDL while increasing HDL, indicating improved lipid metabolism. Oxidative stress markers, such as malondialdehyde (MDA), were reduced, and antioxidant gene expression (SOD1) was upregulated in l-carnitine-supplemented groups. Emulsifiers enhanced fat digestion, as evidenced by increased lipase activity and CPT1/CPT2 gene expression. Combined treatments showed no consistent additive effects. It is concluded that dietary supplementation with l-carnitine and emulsifiers enhances growth performance and lipid metabolism in broilers raised at high altitudes. While l-carnitine enhances antioxidant capacity, reduces oxidative stress, and improves cardiopulmonary health, emulsifiers do not directly affect oxidant and antioxidant status but optimize lipid parameters.

01 Jul 2025·Industrial Crops and Products

Priming effects of gamma radiation on the mitigation of drought stress: The morpho-physiological responses of Oenothera speciosa Nutt

Author: Bagheri, Leila ; Sabzalian, Mohammad R. ; Hadipanah, Amin ; Shabani, Leila

Radiation-induced priming is a potent method for improved stress tolerance under adverse conditions, such as drought.Therefore, this experiment was conducted to investigate the morphol. and physiol. responses and drought tolerance indexes of Oenothera speciosa genotypes exposed to different doses of gamma rays and to determine the appropriate dose of radiation for the use in drought stress tolerance programs in this species.Seeds from three genotypes of O. speciosa were exposed to different levels of gamma radiation, including 50, 100, 200, and 300 Gy for 21′ 22", 42′ 44", 85′ 28" and 128′ 12", resp.Then, treated seeds were sown in pots, grown in the greenhouse, and transferred to the field.The field experiment was carried out based on a randomized complete block exptl. design with three replications for 3 mo.The plants were irrigated weekly under normal conditions until the early flowering stage.Afterward, irrigation continued to maintain the min. soil moisture at 50 % (normal condition) and 15 % (drought condition) of field capacity for two months.The growth and physiol. traits associated with tolerance to drought stress of plants were examined from the flowering stage onward.The study revealed a notable rise in plant height, fresh weight, thousand-grain weight, flowers per plant, seed yield, total carbohydrate content, DPPH radical scavenging capacity, anthocyanin content, ascorbate and glutathione contents, oil content, and a significant drop in electrolyte leakage, H₂O₂, and malondialdehyde contents in all 3 genotypes of O. speciosa, exposed to all gamma irradiation levels, under both drought and normal irrigation conditions.In addition, OS3 was the best genotype responding to gamma irradiation related to its higher seed yield and plant dry weight-based drought tolerance indexes.According to the results of the present study, it is concluded that the impacts of O. speciosa seed priming with gamma radiation may result in a significant increase in tolerance to drought stress conditions.

01 Jul 2025·Journal of Molecular Structure

Impact of β-carotene on the structural and thermal behavior of β-lactoglobulin: A study integrating spectroscopy, docking, and MD

Author: Majrashi, Taghreed A. ; Farhadian, Sadegh ; Shareghi, Behzad ; Evini, Mina ; Alghamdi, Sami Saad ; Atiya, Akhtar ; Assaran-Darban, Reza ; Yousefi, Bahareh ; Alshehri, Saad Ali ; Gholizadeh, Mohammad ; Roshanzamir, Muhammad

This research studied the interaction between the milk protein beta-lactoglobulin (β-Lg) and beta-carotene (βC) using a combination of exptl. and computational techniques.UV-visible spectroscopy was employed to study the binding characteristics of the βC-(β-Lg) complex, revealing an interaction between the two mols.The spectrofluorometric method was used to further elucidate the binding mechanism as a hydrophobic interaction, where the Stern-Volmer constant (Ksv) and the quenching rate constant (Kq) were determined, indicating a static quenching mechanism (Kq> 2 x 10¹⁰ L mol^-1 s^-1).Hydrophobic interactions are suggested by a pos. ΔH° (24.53 kJ/mol^-1) and a pos. ΔS° (86.46 J/mol^-1. K^-1). ΔG° for 298, 308, and 318 K are, resp., -13.85, -17.81, -31.35 kJ/mol^-1.The binding constants are 2.69 x 10³,11.86 x 10³, and 14.19 x 10³ M^-1, resp.Thermal denaturation studies confirmed the increased stability of the βC-(β-Lg) complex.CD and FTIR spectroscopy results demonstrated that the binding of βC induces conformational alterations.Atomic-level studies, including RMSD, RG, RMSF, SASA, and ASA values, provided detailed insights into the binding pose, intermol. interactions, compactness, and stability between β-Lg and βC, corroborating the exptl. findings.The results contribute to understanding the structural and binding properties of this protein-carotenoid system, which may have implications for its potential applications in the food and pharmaceutical industries.

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