[Translation] A phase Ia randomized, double-blind, placebo-controlled, single-dose, dose-escalation clinical trial of tolerability and pharmacokinetics of Akanin B drops in healthy humans
观察健康受试者对单次给药的阿卡宁B滴丸的安全性和耐受性,并对单次给药的药代动力学进行初步探索,为多次连续给药的耐受性试验、药代动力学试验及II期临床试验给药方案提供安全的剂量范围及参考依据。
[Translation] To observe the safety and tolerability of a single dose of Akanin B pills in healthy subjects, and to conduct a preliminary exploration of the pharmacokinetics of a single dose, so as to provide a safe dosage range and reference basis for tolerance tests, pharmacokinetic tests and dosing regimens of phase II clinical trials of multiple continuous doses.