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A Phase I, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of DAT-2645 in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DNA Damage Repair Pathway
The primary objective of the study is to evaluate the safety, tolerability, PK, PD, and prilimary efficacy of a PARG inhibitor DAT-2645 in patients with advanced/metastatic solid tumors harboring BRCA1/2 loss of function alterations and/or other defects in the DNA damage repair (DDR) pathway.
100 Clinical Results associated with Beijing Danqing Pharmaceutical Technology Co., Ltd.
0 Patents (Medical) associated with Beijing Danqing Pharmaceutical Technology Co., Ltd.
100 Deals associated with Beijing Danqing Pharmaceutical Technology Co., Ltd.
100 Translational Medicine associated with Beijing Danqing Pharmaceutical Technology Co., Ltd.