[Translation] A randomized, double-blind, parallel-controlled, dose-finding phase II clinical trial of Yishen Huazhuo granules combined with valsartan capsules in the treatment of chronic renal failure with qi and yin deficiency, dampness, turbidity and blood stasis syndrome.
1.初步评价益肾化浊颗粒延缓慢性肾功能衰竭进展的作用。
2.初步评价益肾化浊颗粒与缬沙坦胶囊合用对慢性肾功能衰竭的证候改善作用。
3.探索益肾化浊颗粒治疗慢性肾功能衰竭的合理剂量。
4.观察益肾化浊颗粒的安全性及不良反应。
[Translation] 1. To preliminarily evaluate the effect of Yishen Huazhuo Granules in delaying the progression of chronic renal failure.
2. To preliminarily evaluate the effect of Yishen Huazhuo Granules combined with valsartan capsules on improving the symptoms of chronic renal failure.
3. To explore the reasonable dose of Yishen Huazhuo Granules in the treatment of chronic renal failure.
4. To observe the safety and adverse reactions of Yishen Huazhuo Granules.