Guizhou Shengjitang Pharmaceutical Co., Ltd.

Primary objective: To investigate the bioequivalence of the two preparations in healthy subjects, using the tadalafil tablets (specification: 20 mg) of Guizhou Shengjitang Pharmaceutical Co., Ltd. as the test preparation and the tadalafil tablets (specification: 20 mg) of Eli Lilly Nederland B.V. as the reference preparation according to the relevant provisions of the bioequivalence test. Secondary objective: To observe the safety of the test preparation and the reference preparation in healthy subjects.

Primary objective: To conduct a human bioequivalence study in the fasting and fed state using Donepezil Hydrochloride Tablets (Specification: 5 mg) produced by Guizhou Shengjitang Pharmaceutical Co., Ltd. as the test preparation and Aricept® produced by Eisai (China) Pharmaceutical Co., Ltd. as the reference preparation, and to evaluate the bioequivalence of the test preparation and the reference preparation. Secondary objective: To observe the safety of the test preparation and the reference preparation in healthy subjects in the fasting and fed state.

Main purpose: To conduct a human bioequivalence study in the fed state using venlafaxine hydrochloride tablets (specification: 50 mg (calculated as C17H27NO2)) produced by Guizhou Shengjitang Pharmaceutical Co., Ltd. as the test preparation and venlafaxine hydrochloride tablets (specification: 50 mg (calculated as C17H27NO2)) produced by TEVA Czech Industries, s.r.o. as the reference preparation, and evaluate the bioequivalence of the test preparation and the reference preparation. Secondary purpose: To observe the safety of the test preparation and the reference preparation in healthy subjects in the fed state.