Jiangsu Ruishi Biotechnology Co., Ltd.

Main research purpose: According to the relevant provisions of bioequivalence test, the pediatric faropenem sodium granules (trade name: Feroum, specification: 0.05g (calculated in C12H15NO5S)) of Maruho Co., Ltd. as the licensee was selected as the reference preparation, and the test preparation pediatric faropenem sodium granules (specification: 0.05g (calculated in C12H15NO5S)) produced by Tianda Pharmaceutical (Zhuhai) Co., Ltd. and provided by Jiangsu Ruishi Biotechnology Co., Ltd. were subjected to fasting and postprandial human bioequivalence tests to compare whether the absorption rate and degree of the drug in the test preparation were within the acceptable range with the reference preparation, and to evaluate the bioequivalence of the two preparations under fasting and postprandial administration conditions. Secondary study objectives: To observe the safety of oral administration of the test preparation, pediatric faropenem sodium granules (specification: 0.05g (calculated as C12H15NO5S)) and the reference preparation, pediatric faropenem sodium granules (trade name: Feromu, specification: 0.05g (calculated as C12H15NO5S)) to healthy volunteers To evaluate the palatability of pediatric faropenem sodium granules in healthy Chinese subjects and provide a basis for the taste of pediatric faropenem sodium granules.

Primary objective: To compare the differences in the extent and rate of absorption of paroxetine hydrochloride tablets (20 mg/tablet) provided by Jiangsu Ruishi Biotechnology Co., Ltd. and paroxetine hydrochloride tablets (20 mg/tablet, trade name: Paxil®) certified by Apotex Technologies Inc. in healthy adults under fasting and postprandial administration conditions, and to evaluate their bioequivalence. Secondary objective: To evaluate the safety of paroxetine hydrochloride tablets (20 mg/tablet) provided by Jiangsu Ruishi Biotechnology Co., Ltd. and paroxetine hydrochloride tablets (20 mg/tablet, trade name: Paxil®) certified by Apotex Technologies Inc. in healthy adults.