Q1 · MEDICINE
Article
Author: Ghosh, Manali ; Bellail, Anita C. ; Kim, Daeho ; Shekhar, Anantha ; Hamdouchi, Chafiq ; Mosley, Amber L. ; Jung, Sung Han ; Lo, Ho-Yin ; Hao, Chunhai ; le Sage, Carlos ; Zhao, Yin Quan ; Blanck, Maximilian ; Li, Jing ; Hauck, Paula M. ; Jiang, Wen ; Higgins, Ryan K. ; Jin, Hong Ri ; Cross, Benedict C.S. ; Wijeratne, Aruna B.
Small-molecule degraders of SUMO1 induce its ubiquitination and degradation through binding of CAPRIN1 in tumor cells in vitro and in vivo.