Effect of Uncaria Tomentosa Supplementation on Markers of Inflammation and Oxidative Stress, Pain, and Quality of Life in Women with Endometriosis: A Randomized, TripleBlind, Placebo-Controlled Clinical Trial

Start Date01 Apr 2025

Sponsor / Collaborator

Fundação Universidade Federal de Sergipe

[+1]

RBR-4w44wkd

/ Active, not recruitingPhase 1IIT

Evaluation of a semi-solid formulation containing a combination of free and nanoencapsulated natural products for protection against solar radiation

Start Date01 Oct 2024

Sponsor / Collaborator

Fundação Universidade Federal de Sergipe

[+1]

RBR-89svjw3

/ Active, not recruitingNot ApplicableIIT

Effect of Functional Training on cognitive health and functional independence in postmenopausal women with Cognitive Impairment

Start Date04 Mar 2024

Sponsor / Collaborator

Fundação Universidade Federal de Sergipe

[+1]

100 Clinical Results associated with Fundação Universidade Federal de Sergipe

0 Patents (Medical) associated with Fundação Universidade Federal de Sergipe

12,824

Literatures (Medical) associated with Fundação Universidade Federal de Sergipe

01 Feb 2025·Biomass Conversion and Biorefinery

Influence of potassium-based catalysts in the pyrolysis of Caupi bean pod (Vigna unguiculata): bio-oil characterization by gas chromatography coupled with mass spectrometry (GC/MS) and comprehensive two-dimensional gas chromatography (GC × GC/TOFMS)

Author: Ramos, Andre Luis D. ; Santos, Roberta Menezes ; Freitas, Lisiane Santos ; von Muhlen, Carin ; Bispo, Diego Fonseca ; Mazza, Felipe Cury ; Santos, Laryssa Meneghel

The Caupi bean pod (Vigna unguiculata) is an agricultural residue with the potential to be used in the pyrolysis process, as it contributes to minimize the environmental impact and add value to this material.In situ catalytic pyrolysis, in which the catalysts and feedstock were kept in one reactor, was performed with five different potassium catalysts, and their catalytic effect on the bio-oils composition distribution and phenols enrichment was evaluated.The bio-oils obtained were characterized by gas chromatog. coupled with mass spectrometry (GC/MS) and comprehensive two-dimensional gas chromatog. with time-of-flight mass spectrometry GC x GC/TOFMS.The application of GC x GC/TOFMS was important to resolve coeluted peaks from the GC/MS anal., resulting in a different distribution of compounds by chem. classes.This affected the percentual area of the phenols group, since it ranged from 44.28 to 65.78% with GC/MS anal., while the area from the same group varied from 59.77 to 73.75% in the GC x GC/TOFMS anal. of the same samples.The bio-oils produced were characterized, and the data showed that K⁺ and anions affected primary and secondary reactions, modifying the formation of several chem. species.The catalytic pyrolysis of the bean pod showed a strong tendency to produce high yields and selectivities of phenols and their derivatives due to the performance of the acids catalysts.This work demonstrated that the potassium ion (K⁺) acts to improve the quality of bio-oil from the pyrolysis of cowpea pods (Vigna unguiculata), as well as a greater or lesser synergistic effect of counterions in enhancing the bio-oil quality.This contributes to the formation of com. valuable compounds, such as phenols and their derivatives

01 Feb 2025·Biomass Conversion and Biorefinery

Bio-oil as a source of renewable chemicals: the chemistry of pyrolytic lignin

Author: Dahmen, Nicolaus ; Raffelt, Klaus ; Santos, Tarcisio Martins ; Wisniewski, Alberto Jr ; Silva, Wenes Ramos ; Schmitt, Caroline Carriel ; Carregosa, Jhonattas Carvalho

Abstract: Pyrolytic lignin from beech wood bio-oil was fractionated into low mol. mass (LMM) and high mol. mass (HMM).A comprehensive characterization by FTIR, GPC, TG, GC/MS, and multidimensional NMR spectroscopy was employed to analyze the individual fractions.Addnl., advanced characterization was carried out using ultra-high-resolution mass spectrometry (UHRMS).The data reveal that the LMM fraction has a higher prevalence of phenolic monomers due to homolytic cleavage of the RC-OAr linkage in aryl-O-alkyl ether bonds corroborating with GC/MS results.On the other hand, the HMM fraction shows a higher d.p. and a wider mol. mass distribution, predominantly comprising carbohydrate derivatives by GC/MS.UHRMS data proved to be valuable in characterizing the monomers and oligomers present in each fraction, offering insights for future applications and the development of value-added products.Overall, this work significantly advances the current knowledge of pyrolytic lignin structures, opening opportunities for innovative technol. bioproducts.Graphical abstract: [graphic not available: see fulltext]

01 Jan 2025·Biomass Conversion and Biorefinery

Green solvent-assisted hydrothermal conversion of biomass waste into bio-oil under pressurized conditions

Author: Romero, Romina ; Loeser, Thiago Ferreira Leao ; Bispo, Diego Fonseca ; Alejandro-Martin, Serguei ; Cardozo-Filho, Lucio ; dos Santos Freitas, Lisiane ; Jegatheesan, Jega

Abstract: This study investigates the effects of hydrothermal treatment combined with acetic acid on the distribution of products in bio-oil obtained from grape seed pyrolysis.A Box-Behnken exptl. design was employed, varying pH (2.0, 4.5, and 7.0), temperature (160, 180, and 200 °C), and flow rate (1, 2, and 3 mL·min^-1) to determine the hydrothermal treatment′s impact on product distribution.A pyrolysis-gas chromatog./mass spectrometry system was used to perform pyrolysis of hydrotreated biomass and analyze product compositionOptimized models revealed that different process conditions favored distinct compound types.For example, increased temperature and decreased pH and flow rates enhanced hydrocarbon presence, achieving 32.3% abundance compared to 1.15% in untreated biomass.Conversely, oxygenated compounds such as ketones and aldehydes were optimized at high flow rates, milder temperatures, and low/high pH, reaching 66.7% abundance compared to 42.6% for untreated biomass.This work stands out for the green solvent-assisted hydrothermal processing of grape seeds, adding value to a low-applicability agro-industrial residue.It reduces process toxicity and results in a significant increase in the presence of hydrocarbons in the bio-oil, representing a promising approach for converting biomass waste into valuable bioproducts with potential applications in the chem. and fuel industry.It also demonstrates the potential scalability of this technol.These innovative aspects are relevant to waste management and the search for sustainable sources of energy and chems.Graphical Abstract: [graphic not available: see fulltext]

100 Deals associated with Fundação Universidade Federal de Sergipe

100 Translational Medicine associated with Fundação Universidade Federal de Sergipe

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