Sinocelltech Group Ltd.

The dynamics of the esophageal cancer market are predicted to grow owing to the increasing prevalence of cancer and the increase in research & development. In addition, the anticipated launch of emerging therapies will also propel the esophageal cancer market growth in the coming years. LAS VEGAS, July 6, 2023 /PRNewswire/ -- DelveInsight's Esophageal Cancer Market Insights report includes a comprehensive understanding of current treatment practices, esophageal cancer emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan]. Key Takeaways from the Esophageal Cancer Market Report As per DelveInsight analysis, the esophageal cancer market size in the 7MM was approximately USD 1,000 million in 2022. According to the assessment done by DelveInsight, the estimated total diagnosed incident esophageal cancer cases in the US were approximately 20K in 2022. Globally, leading esophageal cancer companies such as Zymeworks, Innovent Biologics, BeiGene, Apexigen, Shanghai Henlius Biotech, CStone Pharmaceuticals, Jiangsu HengRui Medicine Co., Ltd., AstraZeneca, Symphogen, Hoffmann-La Roche, Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Sinocelltech Ltd., Eli Lilly and Company, Ipsen, Jacobio Pharmaceuticals Co., Ltd., Shire, GlaxoSmithKline, Keythera Pharmaceuticals (Australia) Pty Ltd, Sunshine Lake Pharma Co., Ltd., Novartis Pharmaceuticals, Sanofi, Seagen Inc., Rapa Therapeutics LLC, Incyte Corporation, Atreca, Inc., Exelixis, Bayer, Lyell Immunopharma, Sichuan Baili Pharmaceutical, AP Biosciences., Leap Therapeutics, Inc., Adlai Nortye Biopharma Co., Ltd., Athenex, Inc., Pfizer, Genentech, Hangzhou Neoantigen Therapeutics, Janssen Pharmaceutical, Curis, Inc., Merck KGaA, Shenzhen Hornetcorn Bio-technology Company, LTD, MacroGenics, Bristol-Myers Squibb, Integral Molecular, CARTEXELL, EMD Serono, and others are developing novel esophageal cancer drugs that can be available in the esophageal cancer market in the coming years. The promising esophageal cancer therapies in the pipeline include Zanidatamab, Sintilimab, Tislelizumab, Sotigalimab (APX005M), and others. Discover which therapies are expected to grab the major esophageal cancer market share @ Esophageal Cancer Market Report Esophageal Cancer Overview Esophageal cancer arises when cancer cells originate in the esophagus, a tube-like tissue that connects the throat and stomach. The esophagus transfers food from the mouth to the stomach. The cancer develops in the inner layer of the esophagus and can spread to other layers of the esophagus and other organs of the body. Typically, signs of esophageal cancer do not develop until the tumor has grown large enough to obstruct eating, swallowing, or digesting food. The most common symptom of esophageal cancer is difficulty swallowing, specifically a sense that food is trapped in the throat; in some cases, choking on food occurs. These symptoms worsen with time, with increasing discomfort while swallowing as the esophagus narrows due to cancer growth. Indications or symptoms of esophageal cancer are frequently used to diagnose it. Exams, testing, and a biopsy will be required to confirm the diagnosis; if cancer is found, additional tests will be performed to determine the extent. Esophageal Cancer Epidemiology Segmentation DelveInsight estimates that there were approximately 20K diagnosed incident cases of esophageal cancer in the US in 2022. In 2022, as per the age-specific cases, the 65 and above segment accounted for the highest number of cases of esophageal cancer. In contrast, the <45 age group accounted for the least number of cases in the United States. The esophageal cancer market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into: Total Esophageal Cancer Diagnosed Incident Cases Esophageal Cancer Age-specific Cases Esophageal Cancer Histology-specific Cases Esophageal Cancer Gender-specific Cases Esophageal Cancer Mutation-specific Cases Esophageal Cancer Stage-specific Cases Esophageal Cancer Line-wise Treated Cases Esophageal Cancer Treatment Market Everyone with esophageal cancer is treated in some way. The best course of therapy for each patient is determined by a number of criteria, including personal preferences, cancer stage, and overall health. Many medical specialists work together on a daily basis in cancer care to create a patient's comprehensive treatment plan, which includes a variety of treatments. Esophagectomy is the primary esophageal cancer treatment for early-stage esophageal cancer, while its precise role in superficial (T1A) malignancies remains unknown, owing to the introduction of endoscopic mucosal therapy. A multimodal strategy of neoadjuvant chemotherapy or combination chemoradiotherapy (CRT) followed by surgery is strongly recommended for treating locally advanced malignancies. Preoperative evaluation is the cornerstone of modern esophageal cancer management. The precision and specificity of the clinical staging evaluation will be dependent on the tumor board's recommendations on the use of multimodal therapy, thus preoperative staging accuracy is crucial. The standardized evaluation of a patient undergoing curative treatment for early-stage or advanced esophageal cancer includes upper endoscopy, high-resolution contrast CT scan, FDG-PET scan, and EUS. For a tumor that has not migrated beyond the esophagus and lymph nodes, doctors often recommend a combination of radiation treatment, chemotherapy, and surgery. Locally advanced esophageal cancer is typically treated with radiation therapy, chemotherapy, and surgery. Radiation treatment and chemotherapy are frequently combined in "chemoradiotherapy." Radiation therapy, chemotherapy, and other drug-based therapies are frequently used to treat metastatic esophageal cancer. To know more about esophageal cancer treatment, visit @ Esophageal Cancer Treatment Drugs Key Esophageal Cancer Therapies and Companies Zanidatamab: Zymeworks Sintilimab: Innovent Biologics Tislelizumab: BeiGene Sotigalimab (APX005M): Apexigen Nivolumab: Bristol-Myers Squibb Pembrolizumab: Merck Sharp & Dohme Learn more about the FDA-approved drugs for esophageal cancer @ Drugs for Esophageal Cancer Treatment Esophageal Cancer Market Dynamics The esophageal cancer market is expected to change in the coming years owing to expanding disease awareness and increased healthcare spending around the world, which will increase the size of the esophageal cancer market. The esophageal cancer companies and academics are working to assess challenges and seek opportunities that could influence esophageal cancer R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition. Esophageal cancer companies are involved in developing esophageal cancer therapies. Moreover, the anticipated introduction of emerging therapies with improved efficacy and a further improvement in the diagnosis rate are expected to drive the growth of the esophageal cancer market in the 7MM. However, several factors are impeding the growth of the esophageal cancer market. The cost of newly approved drugs is typically exorbitant, so people avoid correct therapy or opt for off-label and low-priced medications. It has an impact on market access for newly released drugs, and reimbursement is critical. Market access and reimbursement options might vary depending on regulatory status, target population size, care environment, unmet requirements, the volume of extra benefit claims, and costs. Furthermore, the esophageal cancer market growth may be offset by failures and discontinuation of emerging therapies and a shortage of healthcare specialists. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the esophageal cancer market growth. Scope of the Esophageal Cancer Market Report Therapeutic Assessment: Esophageal Cancer current marketed and emerging therapies Esophageal Cancer Market Dynamics: Attribute Analysis of Emerging Esophageal Cancer Drugs Competitive Intelligence Analysis: SWOT analysis and Market entry strategies Unmet Needs, KOL's Views, Analyst's Views, Esophageal Cancer Market Access and Reimbursement Discover more about esophageal cancer drugs in development @ Esophageal Cancer Clinical Trials Table of Contents Related Reports Esophageal Cancer Pipeline Esophageal Cancer Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key esophageal cancer companies, including BeiGene, AstraZeneca, CSPC ZhongQi Pharmaceutical Technology, Amgen, Jiangsu Hengrui Medicine, Oncolys Biopharma, Pfizer, Novartis, Luye Pharma, Eli Lilly and Company, ImmunoFrontier, Inc, Adaptimmune, Innovent Biologics (Suzhou) Co. Ltd., Genentech, Janssen Pharmaceuticals, Merck KGaA, Shenzhen Hornetcorn Biotechnology, Apexigen, Inc., Highlight Therapeutics, EMD Serono, HaiHe Biopharma, Lumicell, Jacobio Pharmaceuticals Co., Ltd., TESARO, Ascentage Pharma Group Inc., Adlai Nortye, Seagen, among others. Gastro-Esophageal Junction Neuroendocrine Tumor (GEJ-NET) Market Gastro-Esophageal Junction Neuroendocrine Tumor (GEJ-NET) Market Insights, Epidemiology, and Market Forecast – 2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key GEJ-NET companies, including Vedanta Biosciences, Inc., Bristol-Myers Squibb, Incyte Corporation, Xencor, Inc., ICON plc, Adaptimmune, Medicenna Therapeutics, Inc., Guangdong Zhongsheng Pharmaceutical Co., Ltd., among others. Esophageal Squamous Cell Carcinoma Pipeline Esophageal Squamous Cell Carcinoma Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key esophageal squamous cell carcinoma companies, including BeiGene, AstraZeneca, Ipsen, Shire, Sanofi, Seagen, among others. Esophageal Squamous Carcinoma Market Esophageal Squamous Carcinoma Market Insights, Epidemiology, and Market Forecast – 2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key esophageal squamous carcinoma companies, including BeiGene, AstraZeneca, Ipsen, Shire, Sanofi, Seagen, among others. About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve . Expand your knowledge and gain valuable insights into personalized cancer care through DelveInsight's Conference Coverage Services Explore some of the conference coverage related case studies: Conference Coverage in Various Oncology Conferences Conference Coverage Intelligence of Asthma and COPD assets across the Respiratory Therapy Area Contact Us Shruti Thakur [email protected] +1(919)321-6187 Logo: SOURCE DelveInsight Business Research, LLP

SHANGHAI, March 31, 2023 /PRNewswire/ -- On March 30, 2023, Apollomics Inc. ("Apollomics"), an innovative biopharmaceutical company and portfolio company of Qiming Venture Partners, listed on Nasdaq through a SPAC merger with Maxpro Capital Acquisition Corp. The combined company is now traded under the symbol APLM with an issue price of $10.00/share and an opening price of $18.60/share, up by 172% at closing price on the first day, representing a market cap of $2.6 billion. Qiming Venture Partners is one of the earliest investors of Apollomics, accompanying the company growth since its Pre-A round. Apollomics' IPO marks Qiming's 5th IPO since 2023. Founded in 2015, Apollomics is committed to the discovery and development of mono- and combination-oncology therapies for cancer treatment. The company has built a pipeline includes nine novel oncology drug candidates, six of which are currently in clinical stage of development. By using targeted therapy, immuno-oncology agents, and other innovative approaches, Apollomics' novel drug candidates have the potential to address a range of cancers, including lung cancer, brain cancer, acute myeloid leukemia, and other solid tumors. The company has achieved breakthroughs in recent years. In 2022, the US FDA has granted Orphan Drug Designation to vebreltinib (APL-101), a highly specific cMet inhibitor, in non-small cell lung cancer and other solid tumors with cMet dysregulation. Apollomics expects results from its global Phase 2 multi-cohort clinical trial this year, which may support its first new drug application with the US FDA while generating clinical data on other indications. Apollomics is also developing uproleselan (APL-106), an E-selectin inhibitor, in China as an adjunct to chemotherapy to enhance its anti-cancer effects for adult patients with relapsed or refractory acute myeloid leukemia. Uproleselan (APL-106) has received Breakthrough Therapy Designation by the US FDA and the China National Medical Products Administration (NMPA). And the company expects to complete patient recruitment of its Phase 3 study in China this year. "Becoming a public company represents a major milestone in our journey to provide solutions for patients with difficult-to-treat cancers worldwide," said Dr. Guo-Liang Yu, Ph.D., Chairman and Chief Executive Officer of Apollomics. "The funds now available to us are expected to facilitate development of our oncology pipeline and further our mission to provide patients with effective therapies and hope." "Apollomics team has been working diligently to develop innovative cancer therapies and has built an extensive pipeline. We believe the successful IPO debut today will help the company further expand clinical trials and invest in research and development, continuously making groundbreaking strides in the field of cancer treatment. The core value of innovative drugs is to address unmet clinical needs, and Qiming will continue to focus on this area, benefiting more patients worldwide." said Nisa Leung, Managing Partner of Qiming Venture Partners. About Qiming Venture Partners Founded in 2006, Qiming Venture Partners is a leading China venture capital firm with offices in Shanghai, Beijing, Suzhou, Hong Kong, Seattle, Boston and the San Francisco Bay Area. Currently, Qiming Venture Partners manages eleven US Dollar funds and seven RMB funds with $9.4 billion in capital raised. Since our establishment, we have invested in outstanding companies in the Technology and Consumer (T&C) and Healthcare industries at the early and growth stages. Since our debut, we have backed over 480 fast-growing and innovative companies. Over 180 of our portfolio companies have achieved exits through IPOs at the NYSE, NASDAQ, HKEX, Shanghai Stock Exchange or Shenzhen Stock Exchange, or through M&A or by other means. There are also over 70 portfolio companies that have achieved unicorn status. Many of our portfolio companies are today's most influential firms in their respective sectors, including Xiaomi, Meituan, Bilibili, Zhihu, Roborock, Gan & Lee Pharmaceuticals, Tigermed, Zai Lab, CanSino Biologics, Schrödinger, APT Medical, New Horizon Health, Venus MedTech, Sanyou Medical, AmoyDx, Berry Genomics, SinocellTech, Yuanxin Technology, Caidya, Belief BioMed, WeRide, Biren Technology and UBTech among many others. SOURCE Qiming Venture Partners

SHANGHAI, Feb. 4, 2023 /PRNewswire/ -- Qiming Venture Partners' portfolio company Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical stage global biopharmaceutical company focusing on novel oral small molecule therapeutics, successfully debuts on Nasdaq on February 3 Beijing Time. It issued at $15.00 per ADS, opened at $25.00 per ADS and up by 66.67%, representing a market cap of $915 million. As an early investor, Qiming first invested in the company's series A round in 2019 and continued to participate in its A+ and B rounds. This successful IPO also marks Qiming's second IPO in 2023. Co-founded by Raymond Stevens, Ph.D., a world-renowned pioneer in the field of structure-based drug discovery, and another Qiming's portfolio company Schrödinger, a leading player in computational physics-based drug design, Structure Therapeutics' platform enables conversion of biologics and peptide therapeutics into orally available small molecule drugs with enhanced pharmaceutical properties, including improved bioavailability and stability by leveraging structure-based drug discovery and computational chemistry expertise. Targeting G-protein-coupled receptors, or GPCRs, Structure Therapeutics currently has a wholly owned pipeline of candidates, including GSBR-1290 targeting GLP-1R, for the treatment of type-2 diabetes mellitus, or T2DM, and obesity, with Phase 1 single ascending dose, or SAD study completed in September 2022, and next generation GLP-1R candidates designed with customized properties to achieve additional benefit. In September 2022, the company completed a Phase 1 SAD and MAD study evaluating ANPA-0073 targeting the apelin receptor, or APJR, for the treatment of patients with diopathic pulmonary fibrosis, or IPF, and pulmonary arterial hypertension, or PAH. It is also advancing a differentiated lysophosphatidic acid 1 receptor, or LPA1R, antagonist for the treatment of IPF. "We are pleased to have been one of the earliest investors and accompanied Structure Therapeutics all the way to the IPO today, a new milestone for the company", said Nisa Leung, Managing Partner of Qiming Venture Partners, "Ever since its inception, Structure Therapeutics has adopted an innovative approach to address current challenges and built a platform to find the best drug candidates. With a global team of experts and their decades of experience, we look forward to Structure Therapeutics further advancing product R&D, commercialization, and corporate development to produce better and more affordable medicines, addressing global unmet needs." About Qiming Venture Partners Founded in 2006, Qiming Venture Partners is a leading China venture capital firm with offices in Shanghai, Beijing, Suzhou, Hong Kong, Seattle, Boston and the San Francisco Bay Area. Currently, Qiming Venture Partners manages eleven US Dollar funds and seven RMB funds with $9.4 billion in capital raised. Since our establishment, we have invested in outstanding companies in the Technology and Consumer (T&C) and Healthcare industries at the early and growth stages. Since our debut, we have backed over 480 fast-growing and innovative companies. Over 180 of our portfolio companies have achieved exits through IPOs at the NYSE, NASDAQ, HKEX, Shanghai Stock Exchange or Shenzhen Stock Exchange, or through M&A or by other means. There are also over 70 portfolio companies that have achieved unicorn status. Many of our portfolio companies are today's most influential firms in their respective sectors, including Xiaomi (SEHK:1810), Meituan (SEHK:3690), Bilibili (NASDAQ:BILI, SEHK:9626), Zhihu (NYSE: ZH, SEHK: 2390), Roborock (SHSE:688169), Gan & Lee Pharmaceuticals (SHSE: 603087), Tigermed (SZSE:300347, SEHK:3347), Zai Lab (NASDAQ:ZLAB, SEHK:9688), CanSino Biologics (SEHK:6185, SHSE:688185), Schrödinger (NASDAQ:SDGR), APT Medical (SHSE:688617), New Horizon Health (SEHK:6606), Venus MedTech (SEHK:2500), Sanyou Medical (SHSE:688085), AmoyDx (SZSE:300685), Berry Genomics (SZSE:000710), SinocellTech (SHSE: 688520), Yuanxin Technology, Caidya, Belief BioMed, WeRide, Biren Technology and UBTech among many others. SOURCE Qiming Venture Partners