[Translation] A single-center, randomized, double-blind, placebo-controlled, dose-escalating phase Ib clinical study to evaluate the safety, tolerability and pharmacokinetics of maleic acid TPN672 tablets in patients with schizophrenia
主要目的: 评估马来酸TPN-672片在精神分裂症患者中多次给药的耐受性和安全性。
次要目的: 评估马来酸TPN-672片在精神分裂症患者中多次给药的药代动力学特征。 探索马来酸TPN-672片对精神分裂症患者情感症状及抑郁症状的疗效。
[Translation] Main objective: To evaluate the tolerability and safety of multiple doses of maleate TPN-672 tablets in patients with schizophrenia.
Secondary objectives: To evaluate the pharmacokinetics of multiple doses of maleate TPN-672 tablets in patients with schizophrenia. To explore the efficacy of maleic acid TPN-672 tablets on affective symptoms and depressive symptoms in patients with schizophrenia.