Jiangxi New Ganjiang Pharmaceutical Co., Ltd.

Main purpose: To compare the pharmacokinetic behavior of the oral test preparation metronidazole tablets (manufacturer: Jiangxi Xin Ganjiang Pharmaceutical Co., Ltd.) and the reference preparation metronidazole tablets (certificate holder: Sanofi, trade name: Flagyl®) in healthy subjects under fasting/postprandial conditions, using pharmacokinetic parameters as the primary endpoint evaluation indicators, and to evaluate whether the two preparations are bioequivalent under fasting/postprandial conditions. Secondary purpose: To observe the safety of the test preparation metronidazole tablets and the reference preparation metronidazole tablets in healthy subjects.

Main purpose: Using pharmacokinetic parameters as the primary endpoint evaluation index, the pharmacokinetic behavior of the test preparation Captopril Tablets provided by Jiangxi Xin Ganjiang Pharmaceutical Co., Ltd. and the reference preparation Captopril Tablets (manufacturer: E. R. Squibb & Sons Limited, trade name: CAPOTENTM) in healthy subjects after oral administration under fasting state was compared to evaluate the bioequivalence of the two preparations. Secondary purpose: Observe the safety of the test preparation Captopril Tablets and the reference preparation Captopril Tablets in healthy subjects.

The bioequivalence of doxylamine succinate tablets (25 mg) manufactured by Jiangxi Xinganjiang Pharmaceutical Co., Ltd. and doxylamine succinate tablets (25 mg) manufactured by CHATTEM INC was evaluated in healthy male and female subjects aged 18 years and above under fasting and postprandial administration conditions, with pharmacokinetic parameters as endpoints.