[Translation] A randomized, open, placebo-controlled, single/multiple-dose, dose-escalating Phase I clinical study to evaluate the safety, tolerability, and pharmacokinetics of YZD-27 for injection in healthy subjects
主要目的:
评价在健康受试者中注射用YZD-27单次和多次给药后的安全性和耐受性。
次要目的:
评价在健康受试者中注射用YZD-27单次和多次给药后的药代动力学特征。
探索性目的:
评价在健康受试者中注射用YZD-27单次给药后尿液和粪便中原型药物及其可能的代谢产物的代谢特征。
[Translation] Primary objective:
To evaluate the safety and tolerability of single and multiple doses of YZD-27 for injection in healthy subjects.
Secondary objective:
To evaluate the pharmacokinetic characteristics of single and multiple doses of YZD-27 for injection in healthy subjects.
Exploratory objective:
To evaluate the metabolic characteristics of the parent drug and its possible metabolites in urine and feces after a single dose of YZD-27 for injection in healthy subjects.