The goal of this clinical trial is to learn if continuous Erector Spinae Plane Block (ESPB) reduces postoperative pain in patients undergoing unilateral thoracotomy. It will also evaluate the safety and effectiveness of continuous ESPB. The total participants needed will be 30 persons. The main questions it aims to answer are:
* Does continuous ESPB lower the intensity of postoperative pain compared to multimodal intravenous analgesia?
* Does continuous ESPB increase the time to first analgesic request?
* Does continuous ESPB reduce the amount of intravenous opioids required in the first 48 hours after surgery?
* Does continuous ESPB improve the overall recovery quality within 48 hours post-surgery?
Participants will:
* Receive continuous ESPB or multimodal intravenous analgesia after the surgery.
* Undergo routine pain assessments, and recovery evaluations using tools like the Visual Analogue Scale (VAS) and Quality of Recovery-15 (QoR-15).
* Participate in follow-up visits for data collection on pain, opioid usage, and recovery quality.

Start Date01 Jan 2025

Sponsor / Collaborator

Universitas Udayana

NCT06784258

/ Active, not recruitingPhase 4IIT

Comparison of Inflammatory Factors, Pain Scale, and Postoperative Recovery Quality (QOR - 15) in Patients Undergoing Colorectal Cancer Surgery with Conventional General Anesthesia Techniques Compared to General Anesthesia Combined with Epidural Anesthesia At Prof. Ngoerah Hospital

Surgery can increase IL-6 cytokines, triggering inflammation and metastasis. The combination of general and epidural anesthesia has the potential to suppress IL-6, improve the tumor microenvironment, provide analgesia, and enhance postoperative recovery.
Objectives :To compare the effectiveness of postoperative analgesia quality in colorectal cancer patients receiving general anesthesia combined with epidural anesthesia.

Start Date28 Dec 2024

Sponsor / Collaborator

Universitas Udayana

NCT06761092

/ Active, not recruitingPhase 4IIT

Nebulized Dexmedetomidine to Reduce Post-Anesthesia Delirium of Sevoflurane in Preschool Children Undergoing Elective Surgery

Analyzing the effectiveness of nebulized dexmedetomidine 2 mcg/kg in reducing the incidence of post-anesthesia delirium in preschool children undergoing elective surgery with sevoflurane inhalation general anesthesia.
Researchers will compare nebulized Dexmedetomidine to a placebo (a look-alike substance that contains no drug) to see if the drug can reduce post anesthesia delirium incidence.

Start Date13 Dec 2024

Sponsor / Collaborator

Universitas Udayana

100 Clinical Results associated with Universitas Udayana

0 Patents (Medical) associated with Universitas Udayana

4,174

Literatures (Medical) associated with Universitas Udayana

01 Jun 2025·Data in Brief

Balinese text-to-speech dataset as digital cultural heritage

Article

Author: Budiantari, Ni Made Julia ; Gunawan, I Made Suma ; Er, Ngurah Agus Sanjaya ; Octavia, Hana Christine ; Kadyanan, I Gusti Agung Gede Arya ; Putra, I Gede Ngurah Arya Wira ; Karyawati, Anak Agung Istri Ngurah Eka

Balinese language has a complex and unique language level system, yet still lacks representation in speech-based technologies such as Text-to-Speech (TTS) and speech recognition. As one of the linguistically rich regional languages, Balinese language digitization efforts have not been optimally developed, limiting research in natural language processing (NLP) as well as the application of regional language-based voice technologies. The limitation of voice-based datasets in Balinese is a major challenge in the development of this technology. Therefore, this research aims to develop a dataset of Balinese native speaker audio recordings covering various language levels to support applications in Text-to-Speech (TTS) systems, speech recognition, and voice-to-text technology. The dataset was developed through a data acquisition process that involved recording the voices of native Balinese speakers of the Badung dialect. Data was collected by recording the voices of native Balinese speakers using the Badung dialect. The resulting recordings were then processed using denoising techniques to improve audio quality, before being categorized based on Balinese politeness levels (Alus Singgih, Alus Sor, Alus Mider, Mider, and Andap) as well as including additional phrases and alphabets to provide a wider variety to the dataset. The results show that this dataset consists of 1187 recordings that reflect a wide range of social variation in Balinese. By providing this resource, this research not only contributes to the development of speech-based technologies, but also plays a role in the preservation of Balinese in the digital age, as well as opening up further research opportunities in NLP for languages with limited resources.

01 Jun 2025·Case Studies in Chemical and Environmental Engineering

Green extraction method and microencapsulation of tannins from young coconut husks-based food waste using gelatin/nanofiber cellulose

Author: Arnata, I. Wayan ; Nitivattananon, Vilas ; Harsojuwono, Bambang Admadi ; Antares, Ardhinata ; Gunam, Ida Bagus Wayan ; Anggreni, Anak Agung Made Dewi ; Wrasiati, Luh Putu

Young coconut husk, a byproduct of food waste, is generated in significant quantities, yet the potential of its bioactive compounds has not been fully explored.This study aims to extract tannins from young coconut husks using an eco-friendly method, optimizing temperature and the gelatin/cellulose nanofiber (NFC) ratio as encapsulants to achieve optimal microcapsule characteristics.The research was conducted in three stages: eco-friendly tannin extraction, optimization of the tannin encapsulation process using response surface methodol. (RSM), and characterization of the microcapsules.Tannin characterization assessed tannin content and yield, while microcapsule examined tannin content, yield, water content, solubility, stability, surface morphol., functional groups, total phenolic, IC₅₀, and antimicrobial activity.The eco-friendly extraction of coconut husk produced tannin content and yielded 14.97 % and 16.35 %, resp.The optimal conditions for tannin microencapsulation were found at 60.64 °C and a gelatin/NFC ratio of 0.69, which achieved maximum tannin content, solubility, and yield while minimizing water content.Tannin microcapsules are more stable at lower pH and temperatureAddnl., thin-layer drying produced microcapsules with higher tannin content, yield, and moisture content than spray drying.The surface morphol. of microcapsules dried in thin layers appeared relatively rough and exhibited non-uniform size compared to those dried with a spray dryer.Anal. of functional groups indicated interactions between the functional groups of tannins and those of gelatin and NFC.Tannin microcapsules demonstrated high total phenolic values, IC₅₀, and antimicrobial activity, suggesting their potential application in broader fields, including the pharmaceutical and food industries, as sources of bioactive compounds

01 May 2025·Home Health Care Management & Practice

Evaluating the Impact of Nurse-led Geriatric Homecare Interventions: A Systematic Review of Randomized Controlled Trials

Author: Wijanadi, M. Candra ; Januraga, Pande Putu ; Gautama, Made Satya Nugraha ; Pendet, Ni Made Diah Pusparini

Nurse-led interventions have gained prominence as a promising approach for geriatric care, yet the existing evidence base remains limited. This systematic review aimed to evaluate the impact of nurse-led home care interventions on health outcomes. Adhering to the PRISMA guidelines, we conducted a comprehensive search of PubMed, ScienceDirect, Scopus, ProQuest, and Embase databases from their inception until April 2024. A narrative synthesis was used. Following the screening of 901 studies derived across five electronic databases, nine trials were analyzed in this review. The interventions showed mixed results on quality of life, with significant improvements in some studies but not others. Physical health and performance generally improved, with fewer falls and better functional status in the intervention groups. Mental health outcomes were also mixed. Caregiver burden did not significantly change overall, but some aspects, such as isolation, improved. Hospitalization rates did not significantly differ between groups in most studies, but emergency department visits were lower in the intervention groups. Mortality rates were also similar between groups, but more patients in the intervention groups died at home. Despite the diversity in approaches, nurses played an active and comprehensive role in all programs. These findings highlight the adaptability and flexibility of nurse-led interventions. Further research is needed to refine these interventions, identify their most effective components, and understand how they can be tailored to meet the unique needs of older adults and their caregivers.

News (Medical) associated with Universitas Udayana

01 Dec 2021

·www.biospace.com

Xlife Sciences AG Appoints New Chief Financial Officer

ZURICH, SWITZERLAND / ACCESSWIRE / December 1, 2021 / Xlife Sciences (XLS DE) announced that Carl von Halem has been appointed as the Company's new Chief Financial Officer, effective as of today, 1 December 2021. Beat Kläui, who has been interim CFO since January 2019, will continue to serve Xlife Sciences as Head Accounting & Tax. Carl von Halem has been Co-Founder and Chief Operating Officer of the Munich-based FinTech company CommneX since September 2016. CommneX's digital tendering and matchmaking platform brings together financial projects of municipalities, public corporations and municipal-related companies with financial partners such as banks, insurance companies and institutional investors. Previously, Carl worked, among others, as Senior Associate for the Berlin-based company SaEnergy Systems, which is active in the field of renewable energies. He holds a degree in economics from the Technical University of Berlin; as part of his studies, he completed an exchange semester at Udayana University Denpasar, Indonesia and a summer school in «Environmental Economics» at the London School of Economics. Oliver R. Baumann, CEO of Xlife Sciences, commented: «With his international education, various stations in the fast-paced and challenging startup environment, the necessary leadership experience and his impressive work ethic, Carl brings the necessary skills to actively support our team and further advance the vision of Xlife Sciences. At the same time, we sincerely thank Beat for his valuable support in the last three years and are very happy that we are able to continue to rely on his wealth of experience.» About Xlife Sciences Xlife Sciences AG is a Swiss company with focus on investing in promising technologies in the life science industry. Xlife Sciences AG is building the bridge from research and development to healthcare markets by supporting researchers and entrepreneurs in positioning, structuring, developing and implementing their concepts. Together with industrial partners or universities, Xlife Sciences AG leads projects through the proof-of-concept phase after an invention disclosure or start-up. Subsequently, the firm focuses on out-licensing or selling the company, often with a combination of a strategic partnership. Xlife Sciences AG offers its investors direct access to the further development of innovative and future-oriented technologies at a very early stage. For more information, please visit: Contact For media inquiries: IRF Reputation AG, Valentin Handschin, handschin@irf-reputation.ch For investor inquiries: Dennis Lennartz, Head Investor Relations, Xlife Sciences AG, Phone +41 44 385 84 60, dennis.lennartz@xlifesciences.ch SOURCE: Xlife Sciences AG View source version on accesswire.com:

100 Deals associated with Universitas Udayana

100 Translational Medicine associated with Universitas Udayana

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