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Last update 07 Mar 2025
Universitas Udayana
Last update 07 Mar 2025
Overview
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Comparison of Inflammatory Factors, Pain Scale, and Postoperative Recovery Quality (QOR - 15) in Patients Undergoing Colorectal Cancer Surgery with Conventional General Anesthesia Techniques Compared to General Anesthesia Combined with Epidural Anesthesia At Prof. Ngoerah Hospital
NCT06761092
Nebulized Dexmedetomidine to Reduce Post-Anesthesia Delirium of Sevoflurane in Preschool Children Undergoing Elective Surgery
100 Clinical Results associated with Universitas Udayana
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01 Apr 2025CHEMOSPHERE
From sea to table: Assessing microplastic contamination in local and non-local salt in Bali, Indonesia
Article
Author: Suteja, Yulianto ; Purnama, Sang Gede ; Dirgayusa, I Gusti Ngurah Putra ; Purwiyanto, Anna Ida Sunaryo
Microplastic contamination in table salt has emerged as a significant environmental and public health concern, particularly in regions like Bali, Indonesia, where salt is predominantly produced through seawater crystallization This study aimed to quantify and characterize microplastics in local and non-local table salts and estimate the potential microplastic intake. A total of 20 salt brands (10 local, 10 non-local) were collected and analyzed using density separation, stereomicroscopy, and FTIR spectroscopy. The results indicated that all salt samples contained microplastics, with an average concentration of 173 ± 119 particles/kg. Non-local salts exhibited higher contamination levels (211 ± 134 particles/kg) compared to local salts (135 ± 88 particles/kg). Fragments were the most prevalent microplastic type (55%), followed by fibers (44%), and smaller particles (≤500 μm) were the most common in size. A total of 13 polymer types were identified in the microplastic samples, with chlorobutyl (33%) and ethylene propylene rubber (29%) being the most dominant. Based on salt consumption rates, it was estimated that Bali residents ingest 1 microplastic particles per day, translating to an annual intake of 316-425 particles. These findings highlight the widespread nature of microplastic contamination in consumable salt and suggest potential health risks from the ingestion of microplastics, which may carry harmful pollutants. The study emphasizes the need for improved salt production practices, stricter pollution controls, and further research into the health implications of microplastic ingestion.
01 Feb 2025World Journal of Oncology
Survival Analysis of Anaplastic Thyroid Carcinoma With Various Therapeutic Modalities: Twenty-Seven Years’ Experience in a Single Cancer Center
Article
Author: Saputra, I Putu Gede Septiawan ; Sudarsa, I Wayan ; Setiawan, I Gede Budhi ; Adiputra, Putu Anda Tusta
Background:
Anaplastic thyroid carcinoma (ATC) is the most aggressive thyroid gland malignancy. Several consensuses support the concept of multimodal therapy that combines surgery, radiation, chemotherapy, and targeted therapy. However, patient's comorbidity, poor performance status, and metastasis often make it impossible for patients to undergo multimodal therapy. Therefore, this study aimed to evaluate the survival analysis of ATC patients with different therapeutic modalities.
Methods:
This study was a retrospective cohort study using data from the Cancer Registry in our institution. All patients with ATC who visited Prof Ngoerah Hospital between 1998 and 2024 were included in this study. Data regarding the survival duration of patients who received treatment modalities, and clinical data were analyzed using SPSS 20.0 with Kaplan-Meier and log-rank tests.
Results:
Forty-two subjects with ATC were included in the analysis, of which 57.1% were female, with a mean age of 62.57 ± 13.42 years old. The median survival is 27.5 days. This study found no association between survival time and clinical characteristics of the patients (P > 0.05). This study found that patients who received combination therapy such as surgery + chemotherapy/radiotherapy (RT) had a longer survival time (64 days), compared to other patients who received surgery only (26 days), chemotherapy/RT only (49 days), or patients who died before receiving any therapy (19 days). However, the log-rank test showed that it was not statistically different (P > 0.05).
Conclusion:
ATC survival rates have remained low, and aggressive strategies are still needed to improve the prognosis.
01 Feb 2025International Journal of Surgery Case Reports
A 25-year neglected giant anterior urethral stone associated with urethral diverticulum and urethrocutaneous fistula: A case report
Article
Author: Muhamad ; Putra, Arief Fadli ; Tirtayasa, Pande Made Wisnu ; Sugianto, Ronald ; Zhafirrahman, M
INTRODUCTION:
Urethral stone (US) is an uncommon disease that may be associated with other conditions. It's interesting if the patient neglected his disease after decades. This case report discusses the giant anterior urethral stone, as well as the neglect in the peripheral area.
PRESENTATION OF CASE:
A 43-year-old man was referred to our hospital with a complaint of scrotal pain 4 days ago. He also complained about weak urine stream, a big-palpable mass, and a small opening in the scrotum that had appeared for many years. There was a history of recurrent urinary pain and purulent urine. Physical examination confirmed a solid-palpable and rounded mass with a meatus in the scrotum. Computed tomography (CT) revealed a giant stone. We performed an open surgery and extracted a 6.8 × 4.5 × 3 cm stone from the bulbous urethra and continued to urethral diverticulectomy.
DISCUSSION:
Neglected US could lead to serious complications if left untreated. This may be caused by lack of knowledge, low socioeconomic status, and negative stigma of urological diseases. Our case became complicated as the patient never came to seek medical help. Geographical and cultural limitations may also contribute to that situation. The current case was found to be more challenging due to limited resources and referral rejection. Finally, this case proved that open surgery can successfully treat the giant US and enhance the quality of life.
CONCLUSION:
Immediate access to health care services in limited resource settings, is essential for early interventions of US in preventing further complications.
100 Deals associated with Universitas Udayana
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100 Translational Medicine associated with Universitas Udayana
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