Delving into the Latest Updates on OxoN Medica, Inc. with Synapse

Overview

Endothelial dysfunction is a multifactorial term in that it encompasses a number of complex biochemical alterations in the ability of endothelial cells to perform their normal physiological function. These alterations are generally initiated by increased oxidative stress leading to pathological alterations in the cellular balance of mediators produced by endothelial cells. The key mediators include nitric oxide (NO), superoxide and endothelin. This review presents the current status of our knowledge of endothelial dysfunction in diabetes and in glaucoma and presents the case for evaluation of multifunctional drugs in these diseases.

01 Jan 2003·Neuroinflammation

Roles of Microglia in Chronic Neurodegenerative Diseases

Author: Wood, Paul L.

A review describes the biochem. characteristics of microglia, focusing on the potential neurotoxic mediators involved in various neurodegenerative diseases and in associated preclin. models of these diseases.

IDrugs

Multifunctional drugs for endothelial dysfunction in diabetes and glaucoma

Author: Wood, Paul L.

A review.Endothelial dysfunction is a multifactorial term in that it encompasses a number of complex biochem. alterations in the ability of endothelial cells to perform their normal physiol. function.These alterations are generally initiated by increased oxidative stress leading to pathol. alterations in the cellular balance of mediators produced by endothelial cells.The key mediators include nitric oxide (NO), superoxide and endothelin.This review presents the current status of our knowledge of endothelial dysfunction in diabetes and in glaucoma and presents the case for evaluation o f multifunctional drugs in these diseases.

100 Deals associated with OxoN Medica, Inc.

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100 Translational Medicine associated with OxoN Medica, Inc.

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Pipeline

Pipeline Snapshot as of 19 Jun 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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