Jiangsu Sihuan Bioengineering Pharmaceutical Co. Ltd.

Primary objective: To investigate the pharmacokinetic characteristics of a single oral dose of 0.5 g (fasting/after meal) of the test preparation Pyrazinamide Tablets (Specification: 0.5 g/tablet, produced by Jiangsu Sihuan Biopharmaceutical Co., Ltd.) and the reference preparation Pyrazinamide Tablets (Specification: 500 mg/tablet, produced by DAVA PHARMACEUTICALS INC) in healthy adult Chinese subjects, and to evaluate the bioequivalence of the two preparations in fasting and after meal conditions. Secondary objective: To evaluate the safety of a single oral dose of 0.5 g (fasting/after meal) of the test preparation and the reference preparation in healthy adult Chinese subjects.