Last update 23 Jan 2025
Advanced Cancer Therapeutics LLC

Advanced Cancer Therapeutics LLC

Holding Company|
2007|
Kentucky, United States
|
< 10
|
www.advancedcancertherapeutics.com

Overview

Tags

Neoplasms
Infectious Diseases
Small molecule drug
Aptamers

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Neoplasms2
Infectious Diseases1
Top 5 Drug TypeCount
Aptamers1
Small molecule drug1
Top 5 TargetCount
NCL(Nucleolin)1
PFKFB3(6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3)1

Related

5
Drugs associated with Advanced Cancer Therapeutics LLC
AS-1411
Target
NCL
Mechanism
NCL inhibitors [+1]
Active Org.
University of LouisvilleUniversity of Louisville [+3]
Originator Org.
The University of Alabama at BirminghamThe University of Alabama at Birmingham
Active Indication
Neoplasms [+1]
Inactive Indication
Advanced Malignant Solid Neoplasm [+4]
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date-
3-PO
Target
PFKFB3
Mechanism
PFKFB3 inhibitors [+1]
Active Org.
University of LouisvilleUniversity of Louisville
Originator Org.
University of LouisvilleUniversity of Louisville
Active Indication
Glioblastoma
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date-
PFK15
Target
PFKFB3
Mechanism
PFKFB3 inhibitors
Active Org.
Advanced Cancer Therapeutics LLCAdvanced Cancer Therapeutics LLC
Originator Org.
Advanced Cancer Therapeutics LLCAdvanced Cancer Therapeutics LLC
Active Indication
Neoplasms
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date-
1
Clinical Trials associated with Advanced Cancer Therapeutics LLC
NCT02044861
/ Unknown statusPhase 1
Phase 1 Open-Label, Dose Escalation, Multi-Center Study of ACT-PFK-158, 2HCl in Patients With Advanced Solid Malignancies
100 Clinical Results associated with Advanced Cancer Therapeutics LLC
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0 Patents (Medical) associated with Advanced Cancer Therapeutics LLC
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100 Deals associated with Advanced Cancer Therapeutics LLC
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100 Translational Medicine associated with Advanced Cancer Therapeutics LLC
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Pipeline

Pipeline Snapshot as of 08 Feb 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Preclinical
1
1
Phase 2 Clinical
Other
3
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
AS-1411
 ( NCL )		Neoplasms
More
Phase 2
PFK15
 ( PFKFB3 )		Neoplasms
More
Preclinical
3-PO
 ( PFKFB3 )		Glioblastoma
More
Discontinued
Selodenoson
 ( A1R )		Atrial Fibrillation
More
Discontinued
PFK-158
 ( PFKFB3 )		Advanced Malignant Solid Neoplasm
More
Pending
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