Zhejiang Hansheng Pharmaceutical Co.,Ltd. of Beisheng Pharma

Main purpose: To compare the absorption rate and extent of the doxofylline tablets provided by Zhejiang Beisheng Pharmaceutical Hansheng Pharmaceutical Co., Ltd. in healthy human bodies with the doxofylline tablets (trade name: ANSIMAR®, reference preparation) certified by ABC FARMACEUTICI S.P.A. according to the relevant provisions of the bioequivalence test, and to investigate the bioequivalence of the two preparations in humans. Secondary purpose: To observe the safety of the test preparation doxofylline tablets and the reference preparation doxofylline tablets (ANSIMAR®) in healthy subjects.

To evaluate the effectiveness and safety of topiramate tablets in reducing uric acid levels in patients with gout compared with allopurinol.

Main purpose: Using dapoxetine hydrochloride tablets (specification: 30 mg (calculated as C21H23NO)) provided by Zhejiang Beisheng Pharmaceutical Hansheng Pharmaceutical Co., Ltd. as the test preparation, according to the relevant provisions of the bioequivalence test, the absorption rate and degree of dapoxetine hydrochloride tablets (trade name: Priligy®/Priligy®, specification: 30 mg (calculated as C21H23NO), reference preparation) certified by Berlin-Chemie AG were compared in healthy humans, and the human bioequivalence of the two preparations was investigated. Secondary purpose: To observe the safety of the test preparation dapoxetine hydrochloride tablets and the reference preparation dapoxetine hydrochloride tablets (Priligy®/Priligy®) in healthy subjects.