[Translation] A single-center, intra-group randomized, double-blind, placebo-controlled clinical trial on the tolerability and pharmacokinetics of oral methosulide film-coated tablets
1.观察健康受试者应用本品的安全性和耐受程度
2.评估健康受试者对本品的安全剂量范围,确定最大耐受剂量(MTD),为II期临床研究推荐安全剂量
3.评价美索舒利薄膜衣片在人体单次和多次给药在人体药代动力学特征
[Translation] 1. Observe the safety and tolerance of this product in healthy subjects
2. Evaluate the safe dose range of this product for healthy subjects, determine the maximum tolerated dose (MTD), and recommend a safe dose for Phase II clinical studies
3. Evaluate the pharmacokinetic characteristics of methosulide film-coated tablets in humans after single and multiple administration