Understanding radiology has always been integral to any interventional procedure. With advances in technology and its applications the breadth and depth of imaging has dramatically increased over the past few years. Therefore, it behooves the interventionalist to have a basic awareness of the various imaging modalities including their strengths and weaknesses, as well as the underlying radiological anatomy, especially in cross section. This knowledge can be helpful in understanding the imaging of the indications for a given procedure, choosing a guidance modality, and for evaluation of the patient who has had a possible complication.