[Translation] A single-center, open-label, randomized, single-dose, four-period, two-sequence, fully repeated crossover bioequivalence study to evaluate the bioequivalence of the test preparation, sodium valproate extended-release tablets (I) (strength: 0.5 g), and the reference preparation, Depakine® (strength: 0.5 g), in healthy adult participants in the fasting and fed state. 
主要研究目的:研究空腹和餐后状态下单次口服受试制剂丙戊酸钠缓释片(I)(规格:0.5 g,以岭万洲国际制药有限公司生产)与参比制剂丙戊酸钠缓释片(I)(德巴金®,规格:0.5 g,赛诺菲(杭州)制药有限公司生产)在健康参与者体内的药代动力学,评价空腹和餐后状态下口服两种制剂的生物等效性。
次要研究目的:评估受试制剂丙戊酸钠缓释片(I)(规格:0.5 g)和参比制剂丙戊酸钠缓释片(I)(德巴金®,规格:0.5 g)在健康参与者中的安全性。
 [Translation] The main purpose of the study is to study the pharmacokinetics of the test preparation sodium valproate extended-release tablets (I) (specification: 0.5 g, produced by Yiling Wanzhou International Pharmaceutical Co., Ltd.) and the reference preparation sodium valproate extended-release tablets (I) (Depakin®, specification: 0.5 g, produced by Sanofi (Hangzhou) Pharmaceutical Co., Ltd.) in healthy participants after a single oral administration in the fasting and fed state, and to evaluate the bioequivalence of the two preparations after oral administration in the fasting and fed state.
Secondary purpose of the study is to evaluate the safety of the test preparation sodium valproate extended-release tablets (I) (specification: 0.5 g) and the reference preparation sodium valproate extended-release tablets (I) (Depakin®, specification: 0.5 g) in healthy participants.