[Translation] A Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of injectable Oba01 in patients with locally advanced/metastatic DR5-positive non-small cell lung cancer
主要目的:评价 Oba01 在局部晚期/转移性非小细胞肺癌患者中的安全性及耐受性,并探索剂量限制性毒性(DLT)和最大耐受剂量(MTD),为 II 期临床试验推荐给药剂量(RP2D)的确定提供依据。
[Translation] Main purpose: To evaluate the safety and tolerability of Oba01 in patients with locally advanced/metastatic non-small cell lung cancer, and to explore dose-limiting toxicity (DLT) and maximum tolerated dose (MTD), and recommend it for phase II clinical trials. Provide a basis for determining the drug dose (RP2D).