Last update 01 Nov 2024

I-Mab Biopharma US Ltd.

Subsidiary Company|
Maryland, United States

Overview

Tags

Neoplasms
Endocrinology and Metabolic Disease
Digestive System Disorders
Monoclonal antibody
Fusion protein
Bispecific antibody

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Neoplasms4
Endocrinology and Metabolic Disease3
Immune System Diseases2
Hemic and Lymphatic Diseases2
Infectious Diseases1
Nervous System Diseases1
Top 5 Drug TypeCount
Monoclonal antibody2
Bispecific antibody1
Fusion protein1
Top 5 TargetCount
CD73(5-nucleotidase)1
4-1BB x CLDN18.21
CD47(Cluster of differentiation 47)1
IL-7Rα(Interleukin-7 receptor subunit alpha)1

Related

5
Drugs associated with I-Mab Biopharma US Ltd.
Lemzoparlimab
Target
CD47
Mechanism
CD47 inhibitors
Active Org.
I-Mab Biopharma US Ltd. [+2]
Originator Org.
I-MAB Biopharma (Shanghai) Co., Ltd.I-MAB Biopharma (Shanghai) Co., Ltd.
Active Indication
Myelodysplastic Syndromes [+6]
Inactive Indication
Bone Marrow Neoplasms [+2]
Drug Highest PhasePhase 3
First Approval Ctry. / Loc.-
First Approval Date-
Uliledlimab
Target
CD73
Mechanism
CD73 inhibitors
Active Org.
I-Mab Biopharma US Ltd. [+2]
Originator Org.
I-MAB Biopharma (Shanghai) Co., Ltd.I-MAB Biopharma (Shanghai) Co., Ltd.
Active Indication
Non-Small Cell Lung Cancer [+8]
Inactive Indication
Neoplasm Metastasis
Drug Highest PhasePhase 2/3
First Approval Ctry. / Loc.-
First Approval Date-
Enoblituzumab
Target
CD276
Mechanism
CD276 inhibitors
Active Org.
MacroGenics, Inc.MacroGenics, Inc.
Originator Org.
MacroGenics, Inc.MacroGenics, Inc.
Active Indication
Localized Prostate Carcinoma
Inactive Indication
Advanced Malignant Solid Neoplasm [+14]
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date-
6
Clinical Trials associated with I-Mab Biopharma US Ltd.
CTR20212803 / RecruitingPhase 2
评价TJ107与帕博利珠单抗注射液联合治疗在局部晚期或转移性实体瘤患者中的安全性和耐受性以及初步疗效的多中心、开放、探索性II期临床研究
[Translation] A multicenter, open, exploratory Phase II clinical study to evaluate the safety, tolerability and preliminary efficacy of TJ107 combined with pembrolizumab injection in patients with locally advanced or metastatic solid tumors
NCT05001347 / CompletedPhase 2
A Phase 2 Clinical Study of TJ004309 in Combination With Atezolizumab (TECENTRIQ®) in Patients With Advanced or Metastatic Ovarian Cancers and Selected Advanced Solid Tumors
NCT04900818 / RecruitingPhase 1
A Phase 1 Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors
100 Clinical Results associated with I-Mab Biopharma US Ltd.
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0 Patents (Medical) associated with I-Mab Biopharma US Ltd.
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100 Deals associated with I-Mab Biopharma US Ltd.
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100 Translational Medicine associated with I-Mab Biopharma US Ltd.
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Pipeline

Pipeline Snapshot as of 07 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Phase 1 Clinical
2
2
Phase 2 Clinical
Other
1
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