KLE Technological University

Microbial fuel cells (MFCs) are regarded as an eco-friendly processes for bioelectricity generation and simultaneously treating wastewater. Nonetheless, MFCs have a significant limitation, constant supply of organics needed for microbial oxidation. In this context, plant microbial fuel cells (PMFCs) play an essential role in addressing this problem. Root exudates containing organic acids and sugars act as continuous electron donors that are metabolized by electrogenic microbes such as Geobacter to drive extracellular electron transfer, while nitrogen-transforming taxa such as Nitrosomonas link substrate oxidation with nitrogen cycling. The present review explores the multiple functions of PMFCs in the concurrent production of energy along with environmental restoration. It outlines the fundamental principles of PMFCs, emphasizing plant selection, microbial diversity, and electrode design as key factors affecting performance. The review also discussed about plant-microbe-electrode interactions in bioelectrogenesis, highlighting their potential in wastewater treatment, soil restoration, and precision agriculture. Furthermore, the review evaluates scalability challenges, including electrochemical limitations, design constraints, and field-level performance in pilot studies. By integrating renewable energy generation with ecosystem services, PMFCs align strongly with multiple United Nations Sustainable Development Goals (UN SDGs), particularly in clean energy, water purification, sustainable agriculture, and climate action. Future advancements in materials science, modular designs, and plant-microbe interactions are essential for translating PMFCs from laboratory prototypes into scalable, multifunctional systems for sustainable development.

Basella alba is a fast-growing succulent perennial runner of family Basellaceae with significant medicinal properties.Basella alba exhibited significant free radical scavenging activity and cytotoxic effects against MCF7 cells line with IC₅₀26.842 ± 0.29 μg/mL and standard doxorubicin exhibited IC₅₀11.5 ± 0.48 μg/mL.It showed the inhibition of COX2 enzyme by reducing the production of prostaglandins with IC₅₀ 11.5 ± 048 μg/mL and standard acetylsalicylic acid exhibited IC₅₀18.1250.22 μg/mL.Biol. databases were accessed to identify phytocompounds and the ADME properties of bioactive compounds were analyzed to determine potential drug-like mols.STRING and KEGG tools were utilized to investigate therapeutically active protein targets and their involvement in breast cancer pathways.From PPI interaction, core genes with maximum node degree were selected to build biol. networks.Highly interacted nodes, phytocompounds, and protein targets were selected for virtual screening.Selection was made to study MMP9 and AKT1 protein targets owing to their involvement in progression and metastasis of cancer.Quercetin demonstrated strongest binding affinity with MMP9, with binding energy of -46.278 ± 15.982 kJ/mol while doxorubicin showed -8 kcal/mol.Betacarotene with AKT1 showed binding energy of -58.626 ± 18.709 kJ/mol while doxorubicin showed -9 kcal/mol.Mol. dynamics and simulation of these complexes showed significant fluctuations indicating stable configuration.

Conventional anal. techniques often rely on harmful chems., leading to significant environmental pollution, contamination, and waste generation.Green anal. chem. aims to develop eco-friendly alternatives, and one of the promising techniques in this field is solid phase microextraction (SPME).As a solvent-free sample preparation method, SPME aligns with the principles of green chem. by eliminating the need for harmful solvents and minimizing waste productionThe versatility of SPME has enabled its effective use in several anal. sample preparation fields including environmental anal., food anal., forensic investigation, pharmaceutical anal., and biomedical research.This technique excels in extracting trace quantities of pharmaceuticals and pesticides from water, soil, and food matrixes.In the pharmaceutical and biomedical sectors, SPME is invaluable for drug discovery, enabling the extraction of drugs and metabolites from biol. samples.This review explored the diverse applications of SPME across multiple disciplines, offering a comprehensive overview of its uses and advancements.It aims to provide valuable insights for researchers, analysts, and industries seeking sustainable approaches in anal. chem., highlighting the potential of SPME for fast, green and efficient practices.