Delving into the Latest Updates on Scotgen Ltd. with Synapse

Overview

Plasma apolipoproteins were determined by a dipstick method based on the technique of immunocapillary migration.Antibodies immobilized on the stick capture apolipoprotein A1 or B from the sample as it migrates.Visualization was performed by using an enzyme-labeled 2nd antibody or an enzyme-labeled apolipoprotein which acts as a tracer.

Isolation of antibody variable region sequences

Author: Hamilton, A. ; Adair, J. ; Weir, N. ; Moss, M. ; Tempest, P. ; Fernie, M. ; Forster, S. ; Armour, K. ; Steven, J. ; King, S. ; Carr, F. ; Wallace, T. P. ; Harris, W. ; King, D. ; White, P. ; Mcgregor, D. ; Turner, A.

The basic steps for isolation of antibody variable region cDNAs from a murine hybridoma are described.Protocols are given for resurrecting mammalian cells from liquid nitrogen, cell culture of hybridoma cells, preparation of RNA from hybridoma cells, preparation of 1st-strand primer-directed cDNA and antibody variable region amplification, and cloning antibody variable region sequences.These protocols can be easily adapted for human antibody variable region cloning.

Production of antibody-based fusion proteins

Author: Hamilton, A. ; Adair, J. ; Weir, N. ; Tempest, P. ; Moss, M. ; Fernie, M. ; Forster, S. ; Armour, K. ; Steven, J. ; King, S. ; Carr, F. ; Wallace, T. P. ; Harris, W. ; King, D. ; White, P. ; Mcgregor, D. ; Turner, A.

A review and discussion with 14 referencesProtocols are presented for the general single-overlap extension PCR (SOE PCR); antibody gene fusion for affinity purification; and screening, anal., and purification of protein fusion products.

100 Deals associated with Scotgen Ltd.

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100 Translational Medicine associated with Scotgen Ltd.

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Pipeline

Pipeline Snapshot as of 26 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

CMV monoclonal antibody(Scotgen [Ceased])	Cytomegalovirus Infections More	Discontinued
Felvizumab ( RSV F protein )	Respiratory Syncytial Virus Infections More	Discontinued