Shanghai Baolong Pharmaceutical Co., Ltd.

The main purpose of the study is to use the diclofenac diethylamine emulsion (specification: 1% (20g: 0.2g, calculated as C14H10Cl2NNaO2)) certified by GSK Consumer Healthcare Schweiz AG as the reference preparation and the diclofenac diethylamine emulsion (specification: 1% (20g: 0.2g, calculated as C14H10Cl2NNaO2)) produced by Baolong Pharmaceutical Co., Ltd. as the test preparation to evaluate the bioequivalence of the two preparations in the fasting state through a single-center, single-dose, randomized, open, two-preparation, three-period, three-sequence, partially repeated crossover design clinical study. Secondary purpose of the study: To observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.

The main purpose of the study is to use the paroxetine hydrochloride enteric-coated sustained-release tablets (trade name: SEROXAT®, 25 mg) certified by GLAXOSMITHKLINE INC. as the reference preparation and the paroxetine hydrochloride enteric-coated sustained-release tablets (25 mg) produced by Baolong Pharmaceutical Co., Ltd. as the test preparation, and to evaluate the bioequivalence of the two preparations in the fasting state through a single-center, randomized, open, single-dose, two-preparation, two-sequence, four-cycle, completely repeated crossover clinical study. Secondary purpose of the study: To observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.

Main research purpose: Using olanzapine tablets licensed by Eli Lilly Nederland B.V. as the reference preparation and olanzapine tablets produced by Powerlong Pharmaceutical Co., Ltd. as the test preparation, a single-center, randomized, open, single-dose, two-cycle, double-crossover clinical study was conducted to evaluate the bioequivalence of the two preparations in the fasting and fed state. Secondary research purpose: Observe the safety of the test preparation and the reference preparation in healthy Chinese subjects.