Last update 02 May 2024
Indena SpA
Last update 02 May 2024
Overview
Basic Info
Introduction Indena is a global leader in the discovery, development, and manufacturing of plant-derived active ingredients for various industries including pharmaceuticals, health supplements, and personal care products. As an Italian corporation, Indena employs approximately 800 individuals, with a dedicated research team of 10%. The company operates in over 70 countries worldwide, with facilities for cultivation, production, and distribution. |
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Neoplasms
Nervous System Diseases
Immune System Diseases
Small molecule drug
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Effect of Nutritional Supplementation With Turmeric on the Cognitive Performance of Subjects With Metabolic Syndrome
Evaluation of a Computational Model That Predicts the Effects of Quercetin on Metabolic Health Using Biological Age and Other Lipid-related Blood Metrics
Profiling Vaccinium macrocarpon components and metabolites in human urine and the urine ex-vivo effect on Candida albicans adhesion and biofilm-formation
100 Clinical Results associated with Indena SpA
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2019NutraCos
Quercefit: from quercetin, a support for human wellbeing
Author: Anonymous
2019Cosmetics
Vitachelox: protection of the skin against blue light-induced protein carbonylation
Author: Togni, Stefano ; Maramaldi, Giada ; Cavagnino, Andrea ; Corti, Ambra ; Giacomelli, Luca
Protein carbonylation (PC) is a marker of reactive oxygen species-mediated alterations induced by external stimuli such as UV and blue light irradiation In this study, we investigated the protective effect of Vitachelox, a mixture of three standardized natural extracts rich in polyphenols, against PC induced by blue light irradiation in human keratinocytes. We tested eight exptl. conditions, including Vitachelox 0.01% and 0.005% w/v, used for 6 or 24 h before irradiation, and a solution of N-acetylcysteine (NAC) as pos. control of protection. PC was evaluated by fluorescence microscopy in situ and by absolute quantification (Carbonyl Score) upon protein extraction and separation Both the in situ visualization study and the carbonyl score showed a considerable increase in protein oxidative damage upon blue light irradiation, and a decrease in PC in the presence of Vitachelox. In particular, Vitachelox 0.005% showed superior results compared to NAC in terms of carbonyl score and protein quality, and it was estimated to exert a protective action against blue-light irradiation ranging from 72% (24 h) to 82% (6 h). The protective antioxidant effect of Vitachelox, together with the anti-inflammatory and anti-microbial properties previously reported, make this natural active ingredient a valuable tool in the maintenance of healthy skin.
2018NutraCos
Cardiovascular health: the role of nutraceuticals and the virtues of bergamot
Author: Palumbo, Cosimo
29 Feb 2024
Gene TherapyDrug Approval
100 Deals associated with Indena SpA
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100 Translational Medicine associated with Indena SpA
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Pipeline
Pipeline Snapshot as of 04 Jul 2024
The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
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1
1
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