Shaoguan University

In response to the challenges posed by the profound integration of generative artificial intelligence(AI)into medical education,this consensus proposes a logically coherent,medically distinctive,forward-looking,and operable AI proficiency framework for medical educators(competency items of medical educators' AI proficiency,CAIP-ME).Through systematic literature review,preliminary framework construction,multiple rounds of expert pre-study,and a structured Delphi method involving extensive consultations with 60 interdisciplinary experts,the core competency items and assessment standards for AI proficiency among medical educators were demonstrated and calibrated.The framework encompasses five core dimensions and 25 specific competency items.The five dimensions are value recognition and ethical foundation,technical understanding and tool application,teaching integration and innovative practice,learning assessment and precise empowerment,and professional development and ecosystem co-construction.Competency items are categorized into 11 foundational competency items essential for all educators and 14 developmental competency items for those pursuing excellence.Each competency item is described in terms of its conceptual definition and key behavioral manifestations,accompanied by observable assessment indicators.This consensus aims to provide a scientific basis for the professional development of medical educators and the faculty building in medical institutions,while establishing a key reference standard for educator competency development in the context of digital transformation in medical education.

Industrial activities have caused widespread arsenic (As) contamination in soil and medicinal crops across southern Asia. This study constructed interplanting systems combing medicinal crops with Pteris vittata L., aiming to mitigate the risk of As exposure in medicinal crops, while simultaneously achieving ecological remediation of contaminated soil. The results revealed that interplanting with P. vittata significantly enhanced the yield of Gynostemma pentaphyllum by 31.90 % (P < 0.05) compared with monoculture systems. Under monoculture conditions, the As concentration in G. pentaphyllum leaves reached 2.34 mg/kg, exceeding the national food safety standard (GB2762-2017, 2 mg/kg). However, interplanting with P. vittata effectively reduced the As concentration in G. pentaphyllum leaves to 1.82 mg/kg. Furthermore, the interplanting of P. vittata with Rhus chinensis significantly inhibited As translocation from belowground to aboveground tissues in R. chinensis. Compared to monoculture, the stem biomass of P. vittata was significantly increased by 57.50 % and 70.32 % when interplanted with G. pentaphyllum and Cassia obtusifolia L. (P < 0.05). So the As enrichment of P. vittata was enhanced in interplanting systems, which is beneficial for the As removal from contaminated soil. The study demonstrated that interplanting primarily regulates plant As uptake through modifications of rhizosphere physicochemical properties and As bioavailability, especially for water-soluble As that is easily absorbed by plants. In conclusion, the interplanting models integrating medicinal crops and P. vittata can achieve the goal of "remediating while producing" in As-contaminated soil.

Phytochemical investigation of roots of Euphorbia ebracteolata Hayata led to ten higher diterpenoids including seven undescribed ones (1-7) and three analogues (8-10), accompanied by four derivatives (7a and 9a-9c) obtained via chemical correlation. Notably, compound 1 represents a rare dinor-ent-isopimarane diterpenoid. Their structures were fully characterized using a combination of spectroscopic, ECD, chemical, and single-crystal X-ray diffraction means. Cytotoxicity screening suggested that the oxidized derivative of 7 (7a) displayed the most potent activity against non-small-cell lung cancer (NSCLC) cell line HCC827, comparable to the positive control, cisplatin. Mechanistic study revealed that 7a could arrest cell cycle at G1/S phase and induce apoptosis.