Delving into the Latest Updates on ANEXT (Shanghai) Biotechnology Co., Ltd. with Synapse

Overview

Tags

Respiratory Diseases

Skin and Musculoskeletal Diseases

Neoplasms

Exosomes

Vaccine

Mesenchymal stem cell therapy

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

No Data

Disease Domain	Count

Neoplasms	2
Infectious Diseases	2
Immune System Diseases	2
Endocrinology and Metabolic Disease	1
Hemic and Lymphatic Diseases	1
Nervous System Diseases	1

Top 5 Drug Type	Count

Exosomes	7
Vaccine	1
Mesenchymal stem cell therapy	1

OBJECTIVESSleep and psychological disorders are common complaints in stroke survivors. The effectiveness of sleep duration in post-stroke on mental well-being and health outcomes has been reported recently. This study aimed to investigate the mediating effect of sleep duration on the relationship between anxiety and health-related quality of life in Chinese post-stroke; MATERIALS AND METHODS: We conducted a quantitative, cross-sectional study with participants recruited through a multistage, stratified, probability proportional to size sampling method. Anxiety, health-related quality of life, and sleep duration were measured by Zung Self-rating Anxiety Scale, World Health Organization Quality of Life Questionnaire, and a self-administered, structured questionnaire. A multiple linear regression analysis was conducted to identify the association between anxiety, sleep duration, and quality of life. The direct and indirect effects of sleep duration on health-related quality of life was assessed using the bootstrap method via Model 4 (parallel mediation) of SPSS PROCESS macro; RESULTS: A total of 856 post-stroke patients participated in the study, and incidence of anxiety symptom amongst post-stroke was 33.53%. Sleep duration mainly plays partial mediating roles in the relationship between mild-to-moderate anxiety and quality of life in physical, psychological, and environment domains, with sleep duration of 7-8h playing a major role; CONCLUSIONS: A significant relationship among anxiety, sleep duration, and quality of life in post-stroke was found in this study. The sleep duration partially mediated the association between anxiety and quality of life. Suitable prevention methods and early interventions for sleep duration may improve the quality of life for post-stroke anxiety.

100 Deals associated with ANEXT (Shanghai) Biotechnology Co., Ltd.

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100 Translational Medicine associated with ANEXT (Shanghai) Biotechnology Co., Ltd.

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Pipeline

Pipeline Snapshot as of 27 Dec 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Discovery

4

5

Preclinical

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

EV-RSV exosome harboring RSV virus fusion protein gene vaccine(ANEXT Biotechnology)	Bacterial lower respiratory infection More	Preclinical
TIME SO-MSC-EXO (ANEXT)	Dermatitis, Seborrheic More	Preclinical
MSC-EXO-II mesenchymal stroma in cellular exosomes combined with thin layer envelope(ANEXT Biotechnology)	Dystrophy, Macular More	Preclinical
XO-CAPSOL-T3 Mesenchymal Cell Exosome	Lung Diseases, Interstitial More	Preclinical
EXO-CAPSOL-T3 Mesenchymal Cell Exosome	Dermatitis More	Preclinical