[Translation] A randomized, double-blind, placebo-controlled, dose-finding, multicenter phase IIa clinical trial of CZ130 capsules in the treatment of nonalcoholic steatohepatitis (damp-heat accumulation type)
主要目的:初步探索不同剂量下CZ130胶囊对非酒精性脂肪性肝炎(湿热蕴结型)患者肝脏炎症的治疗效果;
次要目的:(1)初步探索不同剂量下CZ130胶囊对非酒精性脂肪性肝炎(湿热蕴结型)患者的肝脏脂肪含量变化及肝脏纤维化改善情况;(2)初步探索不同剂量下CZ130胶囊治疗非酒精性脂肪性肝炎(湿热蕴结型)患者的安全性。
[Translation] Main purpose: To preliminarily explore the therapeutic effect of CZ130 capsules at different doses on liver inflammation in patients with nonalcoholic steatohepatitis (damp-heat accumulation type);
Secondary objectives: (1) To preliminarily explore the changes of liver fat content and the improvement of liver fibrosis in patients with nonalcoholic steatohepatitis (damp-heat accumulation type) under different doses of CZ130 capsules; (2) Preliminary exploration of CZ130 capsules under different doses Safety in the treatment of patients with nonalcoholic steatohepatitis (damp-heat accumulation type).