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评估注射用H889A用于全身麻醉下胸腔镜手术后镇痛有效性和安全性的多中心、随机、盲法、安慰剂和阳性药平行对照的Ⅱ期临床研究
[Translation] A multicenter, randomized, blinded, placebo- and active drug-controlled phase II clinical study to evaluate the efficacy and safety of H889A for injection in postoperative analgesia after thoracoscopic surgery under general anesthesia
主要目的:
评价不同剂量注射用H889A用于全身麻醉下行胸腔镜手术后镇痛的有效性,为 Ⅲ 期临床试验剂量选择提供依据。
次要目的:
评价不同剂量注射用H889A用于全身麻醉下行胸腔镜手术后镇痛的安全性。
[Translation] Main purpose:
To evaluate the effectiveness of different doses of H889A for injection for postoperative analgesia in thoracoscopic surgery under general anesthesia, and to provide a basis for dose selection in Phase III clinical trials.
Secondary purpose:
To evaluate the safety of different doses of H889A for injection for postoperative analgesia in thoracoscopic surgery under general anesthesia.
/ Active, not recruitingPhase 1 H889A在肝胆外科手术病人中的药代动力学、安全性、耐受性研究
[Translation] Study on the pharmacokinetics, safety and tolerability of H889A in patients undergoing hepatobiliary surgery
主要目的:评估在肝胆外科手术病人切口内单次给予H889A的药代动力学特征、安全性和耐受性。
次要目的:评估在肝胆外科手术切口内单次给予H889A的有效性。
[Translation] Primary objective: To evaluate the pharmacokinetic characteristics, safety and tolerability of H889A administered as a single dose in the incision of patients undergoing hepatobiliary surgery.
Secondary objective: To evaluate the efficacy of H889A administered as a single dose in the incision of hepatobiliary surgery.
/ Active, not recruitingPhase 1 H889A在骨科手术病人中的药代动力学、安全性、耐受性研究
[Translation] Study on the pharmacokinetics, safety and tolerability of H889A in patients undergoing orthopedic surgery
主要目的:评估在骨科手术病人切口内单次给予H889A的药代动力学特征、安全性和耐受性。 次要目的:评估在骨科手术切口内单次给予H889A的有效性。
[Translation] Primary objective: To evaluate the pharmacokinetic characteristics, safety and tolerability of H889A after a single administration in the incision of orthopedic surgery patients. Secondary objective: To evaluate the efficacy of H889A after a single administration in the incision of orthopedic surgery.
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