Target- |
Mechanism- |
|
|
|
Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date- |
|
|
|
|
|
Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target- |
Mechanism- |
|
|
|
Inactive Indication- |
Drug Highest PhasePreclinical |
First Approval Ctry. / Loc.- |
First Approval Date- |
Early Clinical Study of Allogenic CAR-NK Targeted CD19 (JD010) in the Treatment of Adult Relapsed or Refractory B-cell Malignancies
This is a single-centre, single-arm and open-label study to investigate the safety and efficacy of JD010 in adult patients with relapsed or refractory B cell hematologic malignancies. JD010 injection is a CD19-targeted chimeric antigen receptor modified natural killer cells (CAR-NK) derived from a healthy donor
/ Unknown statusEarly Phase 1IIT Early Clinical Study of Allogenic CD123-CAR-NK Cells (JD023 Injection) in the Treatment of Refractory or Relapsed CD123-positive Acute Myeloid Leukemia
The CD123-Targeted CAR-NK cell therapy is a new treatment that is being investigated for treatment of acute myeloid leukemia (AML). The purpose of this study is to evaluate the safety of CD123-CAR NK cells given to these patients.
/ Not yet recruitingPhase 1 一项评估JD012-CEL注射液治疗晚期实体瘤安全性、耐受性的Ⅰ期临床研究
[Translation] A phase I clinical study evaluating the safety and tolerability of JD012-CEL injection for the treatment of advanced solid tumors.
主要目的:
评价JD012-CEL注射液治疗晚期实体肿瘤的安全性、耐受性。
次要目的:
评价JD012-CEL注射液治疗晚期实体肿瘤的抗肿瘤初步有效性。
探索性目的:
探索JD012-CEL注射液的药代动力学特征;
探索JD012-CEL注射液输注后生物标志物变化。
[Translation] Primary Objective: To evaluate the safety and tolerability of JD012-CEL injection in the treatment of advanced solid tumors.
Secondary Objective: To evaluate the preliminary antitumor efficacy of JD012-CEL injection in the treatment of advanced solid tumors.
Exploratory Objectives: To explore the pharmacokinetic characteristics of JD012-CEL injection; to explore changes in biomarkers after infusion of JD012-CEL injection.
100 Clinical Results associated with Beijing Jingda Biotechnology Co., Ltd.
0 Patents (Medical) associated with Beijing Jingda Biotechnology Co., Ltd.
100 Deals associated with Beijing Jingda Biotechnology Co., Ltd.
100 Translational Medicine associated with Beijing Jingda Biotechnology Co., Ltd.