Delving into the Latest Updates on Guangzhou Baiyunshan Chemical Pharmaceutical Factory with Synapse

Overview

Tags

Infectious Diseases

Respiratory Diseases

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Infectious Diseases	2

Top 5 Drug Type	Count

Small molecule drug	2

Top 5 Target	Count

Bacterial DNA gyrase x TOP	1

Objective: To research crystallization process of azithromycin lactobionate, so as to improve the quality of azithromycin lactobionate.Methods: The influence factors of the crystallization such as temperature, adding rate of antisolvent, amount of seed crystal were analyzed, and the best crystallization process was screened.Results: Under the condition of that add 2% of the seed crystal quantity and the crystallization temperature was during 10-15°C and add the crystallization acetone at 60 min, the content of the products increased 2%, the relevant material fell 1%.Conclusion: Compared with the freeze drying process, the product quality of the optimized crystallization process is obviously superior.

Yaowu Fenxi Zazhi

Simultaneous determination of cephradine and arginine by HPLC

Author: Zeng, Hui ; Liu, Xuebin

Simultaneous determination of cephradine and arginine by HPLC was reported.The Spherisorb C₁₈ column (5 μm, 4.6 mm x 250 mm) was used.The mobile phase consisted of acetonitrile-acetate buffer solution (12:88), the detection wavelength was at 200 nm.7-ADCA (7-aminodesacetoxycephalosporanic acid) and dihydrophenylglycine, and cephalexin had no influence on the assay of the components.

Zhongguo Yiyao Gongye Zazhi

Dichloromethane recovered from ternary solvent systems

Author: Huang, Yan ; Gao, Xiaofen ; Ke, Lingjin ; Wu, Xiongwei

Dichloromethane was recovered from CH₂Cl₂-CH₃OH-H₂O ternary solvent systems, which was the mother liquid of a synthetic antibiotic, by extractive rectification after adding salt.0.15 G mL^-1 KOAc-glycol solution was chosen as the separation agent in this separation process.The purity of the recovered dichloromethane was up to 99.6%.The result showed that it was satisfactory extractive agent, which was economic and easy to be recycled.

100 Deals associated with Guangzhou Baiyunshan Chemical Pharmaceutical Factory

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100 Translational Medicine associated with Guangzhou Baiyunshan Chemical Pharmaceutical Factory

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Pipeline

Pipeline Snapshot as of 27 Jan 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Approved

2

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