Jinan Haitai Medical Technology Co., Ltd.

To evaluate the clinical efficacy and safety of different doses of butoconazole nitrate suppositories in the treatment of vulvovaginal candidiasis and provide a scientific dosage reference for further clinical validation trials.

To conduct a tolerability and clinical pharmacokinetic study of vaginal butoconazole nitrate suppositories in healthy Chinese female subjects to understand the tolerability of this product after vaginal administration as well as the rules of absorption, distribution and elimination, so as to provide a basis for formulating a reasonable dosing regimen for Phase II clinical trials.