The testing for bacterial endotoxin in Cefotaxime Sodium and Tazobactam Sodium was established.The "testing methods for bacterial endotoxin" listed in the appendix of 2005 version of China Pharmacopoeia (II) was used as reference for inference test and result estimationThe maximum free interference sample concentration was 10 mg/mL-1.Under this concentration, the bromhexine hydrochloride has no interfering effect.The bacterial endotoxin test can be used to control Cefotaxime Sodium and Tazcbactam Sodium for Injection.