Haimen Pushi Yiyao

Using budesonide suspension for inhalation produced by Haimen Pushi Pharmaceutical Co., Ltd as the test preparation, and budesonide suspension for inhalation produced by AstraZeneca Pty Ltd (trade name: Pulmicort Respules®/PULMICORT RESPULES®) as the reference preparation, the pharmacokinetic characteristics of the two preparations in healthy volunteers when used once under fasting non-carbon-blocked/carbon-blocked conditions were studied, the analytical methods were verified, the degree of variation was evaluated, the sampling time was optimized, and the corresponding pharmacokinetic parameters were estimated; the safety of single use of the test preparation and the reference preparation in healthy volunteers was observed.